bannerHON
img
HONnews
HONnews
img PATIENT / PARTICULIER img PROFESSIONNEL DE SANTE img WEBMESTRE img
img
 
img
HONcode sites
Khresmoi - new !
HONselect
News
Conferences
Images

Themes:
A B C D E F G H I
J K L M N O P Q
R S T U V W X Y Z
Browse archive:
2019: D N O S A J J M A M F J
2018: D

 
  Other news for:
Autoimmune Diseases of the Nervous System
Pain
Pneumonia
Acquired Immunodeficiency Syndrome
 Resources from HONselect
Prescription Opioids May Raise Pneumonia Risk

By Robert Preidt

THURSDAY, Jan. 10, 2019 (HealthDay News) -- People who take prescription opioid painkillers are at increased risk for pneumonia, especially those with HIV, a new study suggests.

The findings support concerns that prescription opioids can weaken the immune system. Doctors who prescribe opioids need to reduce patients' risk of pneumonia through vaccination and by encouraging them to stop smoking, the researchers said.

For the study, a team from Yale University analyzed data from U.S. patients with and without HIV who were treated at Veterans Affairs medical facilities between 2000 and 2012.

Patients prescribed medium or high doses of opioid painkillers had a higher risk of pneumonia than those who did not take the medications, the findings showed. The risk was highest among those who took immunosuppressive opioids, such as codeine, fentanyl and morphine.

Patients with HIV were more likely to develop pneumonia even when taking low doses of opioids, and especially if they took immunosuppressive opioids, the investigators found.

"We saw that prescription opioids were independently associated with pneumonia requiring hospitalization," said corresponding author Dr. E. Jennifer Edelman, an associate professor at Yale School of Medicine.

Opioids are commonly prescribed to treat pain, especially among patients with HIV, the researchers noted. They believe this is the first study to look at how prescription opioids affect pneumonia risk in patients with HIV.

Prescription opioids can weaken the immune system's ability to fight pneumonia in a number of ways, including by suppressing cough, respiration and mucus secretion, according to the researchers.

The report "lends credence to the hypothesis that opioids have effects on the immune system that are clinically relevant," Edelman said in a Yale news release.

The study was published Jan. 7 in JAMA Internal Medicine.

To reduce the risk of pneumonia, prescribers should consider lower doses of opioids or opioids that do not suppress the immune system, the researchers said. They also suggested that health care providers encourage pneumonia vaccination for patients, especially those with HIV.

More information

The U.S. Centers for Disease Control and Prevention has more on opioids.

SOURCE: Yale University, news release, Jan. 7, 2019

Copyright © 2019 HealthDay. All rights reserved. URL:http://consumer.healthday.com/Article.asp?AID=741260

Resources from HONselect: HONselect is the HON's medical search engine. It retrieves scientific articles, images, conferences and web sites on the selected subject.
Pneumonia
Risk
Research Personnel
Immune System
Pain
The list of medical terms above are retrieved automatically from the article.

Disclaimer: The text presented on this page is not a substitute for professional medical advice. It is for your information only and may not represent your true individual medical situation. Do not hesitate to consult your healthcare provider if you have any questions or concerns. Do not use this information to diagnose or treat a health problem or disease without consulting a qualified healthcare professional.
Be advised that HealthDay articles are derived from various sources and may not reflect your own country regulations. The Health On the Net Foundation does not endorse opinions, products, or services that may appear in HealthDay articles.


Home img About us img MediaCorner img HON newsletter img Site map img Ethical policies img Contact