bannerHON
img
HONnews
HONnews
img PATIENT / PARTICULIER img PROFESSIONNEL DE SANTE img WEBMESTRE img
img
 
img
HONcode sites
Khresmoi - new !
HONselect
News
Conferences
Images

Themes:
A B C D E F G H I
J K L M N O P Q
R S T U V W X Y Z
Browse archive:
2019: A M F J
2018: D N O S A J J M A

 
  Other news for:
Aging
Diabetes Mellitus
Hypertension
Lipoproteins, HDL Cholesterol
 Resources from HONselect
Skin 'Glow' Test Might Someday Spot Disease Risk Early

By E.J. Mundell
HealthDay Reporter

WEDNESDAY, Nov. 21, 2018 (HealthDay News) -- A test that measures wavelengths of light coming off skin cells might detect type 2 diabetes, heart disease and even your risk of dying, new research shows.

It's possible that -- someday -- a quick "autofluorescence" light test to the skin might be used by consumers in "supermarkets, pharmacies or drugstores as a first estimate of [health] risk," according to a Dutch research team.

The new device is called an AGE Reader, with AGE standing for chemicals found on skin cells called "advanced glycation end-products."

AGEs are natural byproducts of illness that can -- using the AGE Reader -- glow or "fluoresce" on the skin, explained the researchers led by Bruce Wolffenbuttel of the University of Groningen.

Their new study tested the device on the skin of nearly 73,000 people whose health was then tracked up to 10 years, with an average follow-up of four years.

During the follow-up period, more than 1,000 participants went on to develop type 2 diabetes, close to 1,300 developed heart disease and 928 died.

A 1-unit rise in skin autofluorescence using the AGE Reader "was associated with a threefold increase in risk of type 2 diabetes or cardiovascular disease, and a five-times increased risk of death," the researchers reported Nov. 21 in the journal Diabetologia.

What's more, the device's power at predicting death or disease remained steady even when telltale risk factors -- such as obesity, high blood pressure, high cholesterol or poor blood sugar control -- were absent, the study found.

Even after adjusting for those risk factors, a 1-unit rise in the AGE Reader autofluorescence score was tied to a 26 percent rise in risk for type 2 diabetes; a 33 percent rise in heart disease risk; and a near-doubling of the odds for death during the follow-up period.

The bottom line is that the new findings support skin autofluorescence "as a first screening method to predict type 2 diabetes, cardiovascular disease and mortality," the researchers said in a journal news release.

One U.S. diabetes specialist was intrigued by the research.

Dr. Gerald Bernstein directs the Friedman Diabetes Program at Lenox Hill Hospital in New York City. He wasn't involved in the new study, but is familiar with "AGE" chemicals as natural indicators of health.

"What's a good example of an AGE that everyone can recognize? On Thanksgiving we put a turkey in the oven with the goal of having a beautiful bird with beautiful browned skin. That browning occurs because of the AGEs in the turkey skin," Bernstein noted.

He explained that in live humans, these proteins "stick to each other and form a web, and this web is an AGE. The formation of AGEs contribute to the complications of diabetes."

Because AGEs can gradually increase over time, doctors might someday "easily screen whole populations by the fluorescent technique to identify who has AGEs and is therefore at risk," Bernstein said.

A heart specialist agreed. Dr. Guy Mintz called the study "impressive," and said devices like the AGE Reader "could be a game-changer in cardiovascular and diabetic risk assessment." He directs cardiovascular health at North Shore University Hospital in Manhasset, N.Y.

Mintz said studies where the AGE Reader was used on a patient's skin before and after medical treatments would be interesting "to see if the pattern of skin autofluorescence changes with medical and lifestyle interventions."

However, Mintz did have one reservation: "I do not agree with the author's [notion] that this technology can be used in nonclinical settings, such as pharmacies, to assess patients' risk." He said non-physicians could easily misinterpret test results and that might harm, not help, patients.

More information

The American Diabetes Association offers more on diabetes.

SOURCES: Gerald Bernstein, M.D., endocrinologist and coordinator, Friedman Diabetes Program, Lenox Hill Hospital, New York City; Guy Mintz, M.D., director, cardiovascular health and lipidology, North Shore University Hospital, Manhasset, N.Y.; Diabetologia, news release, Nov. 21, 2018

Copyright © 2018 HealthDay. All rights reserved. URL:http://consumer.healthday.com/Article.asp?AID=739856

Resources from HONselect: HONselect is the HON's medical search engine. It retrieves scientific articles, images, conferences and web sites on the selected subject.
Risk
Heart
Equipment and Supplies
Research Personnel
Heart Diseases
Death
Blood
Cardiovascular Diseases
The list of medical terms above are retrieved automatically from the article.

Disclaimer: The text presented on this page is not a substitute for professional medical advice. It is for your information only and may not represent your true individual medical situation. Do not hesitate to consult your healthcare provider if you have any questions or concerns. Do not use this information to diagnose or treat a health problem or disease without consulting a qualified healthcare professional.
Be advised that HealthDay articles are derived from various sources and may not reflect your own country regulations. The Health On the Net Foundation does not endorse opinions, products, or services that may appear in HealthDay articles.


Home img About us img MediaCorner img HON newsletter img Site map img Ethical policies img Contact