bannerHON
img
HONnews
HONnews
img PATIENT / PARTICULIER img PROFESSIONNEL DE SANTE img WEBMESTRE img
img
 
img
HONcode sites
Khresmoi - new !
HONselect
News
Conferences
Images

Themes:
A B C D E F G H I
J K L M N O P Q
R S T U V W X Y Z
Browse archive:
2018: N O S A J J M A M F J
2017: D N

 
  Other news for:
Hereditary Diseases
Heart Aneurysm
Coronary Disease
 Resources from HONselect
Study Urges Genetic Testing of Relatives of Aortic Disease Patients

By Robert Preidt

TUESDAY, Aug. 7, 2018 (HealthDay News) -- Many lives could be saved if relatives of patients with aortic diseases underwent routine screening and genetic testing, a new study suggests.

Aneurysms, tears in the lining called dissections and other types of thoracic aortic disease (TAD) are often undetected until they become life-threatening emergencies. At that point, the risk of death is about 80 percent.

The aorta is the main artery that supplies blood from the heart.

In the new study, British researchers found that more than 30 percent of relatives of patients with thoracic aortic disease had a genetic risk for the disease.

"The evidence suggests that screening of first- and second-degree relatives of patients affected by familial non-syndromic TAD, and first-degree relatives of those affected by sporadic TAD will result in a significant number of patients being diagnosed who would otherwise remain unaware they suffer from the disease," said study leader Dr. Giovanni Mariscalco.

This screening "could potentially save lives," Mariscalco, an associate professor in the University of Leicester's cardiovascular sciences department, said in a university news release.

Gareth Owens, chairman of Aortic Dissection Awareness in the United Kingdom and Ireland, said many doctors have believed there is little chance of preventing aortic dissection. "Traditionally, [it] has been regarded by the medical profession as a 'silent killer', striking mainly the over-65s," he said in the release.

"This research shows that there is a significant cohort of up to 30 percent of patients, including many younger patients, in whom a genetic predisposition to aortic dissection can and should be detected through appropriate screening. Prevention is always better than cure," Owens said.

And according to Gavin Murphy, a professor of cardiac surgery at the University of Leicester, a combination of genetic and imaging tests, including echocardiogram, CT-scan and MRI of the aorta, could help identify at-risk patients.

"Now that we have a better idea of the percentage of relatives of people with aortic diseases who are also likely to suffer with the condition, we can start to ascertain the financial viability of introducing routine screening for this at-risk group," Murphy said.

The study was published online recently in the Journal of the American Heart Association.

More information

The Society for Vascular Surgery has more on aortic dissection.

SOURCE: University of Leicester, news release, Aug. 2, 2018

Copyright © 2018 HealthDay. All rights reserved. URL:http://consumer.healthday.com/Article.asp?AID=736480

Resources from HONselect: HONselect is the HON's medical search engine. It retrieves scientific articles, images, conferences and web sites on the selected subject.
Family
Aortic Diseases
Mass Screening
Heart
Aneurysm
Aorta
Risk
The list of medical terms above are retrieved automatically from the article.

Disclaimer: The text presented on this page is not a substitute for professional medical advice. It is for your information only and may not represent your true individual medical situation. Do not hesitate to consult your healthcare provider if you have any questions or concerns. Do not use this information to diagnose or treat a health problem or disease without consulting a qualified healthcare professional.
Be advised that HealthDay articles are derived from various sources and may not reflect your own country regulations. The Health On the Net Foundation does not endorse opinions, products, or services that may appear in HealthDay articles.


Home img About us img MediaCorner img HON newsletter img Site map img Ethical policies img Contact