An autosomal recessive metabolic disorder caused by a deficiency of leading to intralysosomal accumulation of galactolipids such as and . It is characterized by demyelination associated with large multinucleated globoid cells, predominantly involving the white matter of the central nervous system. The loss of disrupts normal conduction of nerve impulses.
Enfermedad de Krabbe /
Esclerosis del Cuerpo Globoide Difuso /
Leucodistrofia de Celulas Globoides /
Enfermedad por Deficiencia de Galactosilceramidasa /