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Inflammatory Musculoskeletal Disorders: Rheumatoid Arthritis
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Description
Arthritis, Juvenile Rheumatoid : Rheumatoid arthritis of children occurring
in three major subtypes defined by the symptoms present during the first
six months following onset: systemic-onset (Still's Disease, Juvenile-Onset)
polyarticular-onset, and pauciarticular-onset. Adult-onset cases of Still's
disease (STILL'S DISEASE, ADULT-ONSET) are also known. Only one subtype
of juvenile rheumatoid arthritis (polyarticular-onset, rheumatoid factor-positive)
clinically resembles adult rheumatoid arthritis and is considered its
childhood equivalent. [1]
Tumor Necrosis Factor :
Serum glycoprotein produced by activated macrophages and
other mammalian mononuclear leukocytes which has necrotizing activity against
tumor cell lines and increases ability to reject tumor transplants. It mimics the
action of endotoxin but differs from it. It has a molecular weight of less than
70,000 kDa.
[1]
[1]
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