Primary Motility Disorders of the Esophagus
The Esophageal
Mucosa
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Esophagogastric Junction
Barrett's
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H.J. Stein
The Esophageal Mucosa
/
Strategy of investigations
What may be expected from the new manometric techniques based on the three-dimensional sphincter pressure profile?
H.J.
Stein
(Munich)
The Esophageal Mucosa
/
Indications for surgery
Are motility disturbances secondary to reflux and can improvement be anticipated after effective treatment?
H.J.
Stein
(Munich), T.R.
DeMeester
(Los Angeles)
The Esophageal Mucosa
/
Nissen fundoplication
Do we know why only certain antireflux valves come undone?
H.J.
Stein
, J.R.
Siewert
(Munich)
The Esophageal Mucosa
/
Nissen fundoplication
The endoscopy should be performed by the surgeon, especially in recurrences
H.J.
Stein
, J.R.
Siewert
, H.J.
Dittler
(Munich)
The Esophageal Mucosa
/
Nissen fundoplication
What are the causes of failure of Nissen's operation?
H.J.
Stein
, J.R.
Siewert
, H.
Feussner
(Munich)
The Esophageal Mucosa
/
Physiopathology
Does esophageal dysfunction in CLE influence bolus propulsion through the esophagus? Does it differ from that of reflux esophagitis?
H.J.
Stein
(Munich), T.R.
DeMeester
(Los Angeles)
Primary Motility Disorders of the Esophagus
/
Diffuse esophageal spasms (Corkscrew esophagus)
The numerous causes which may give rise to DES call for caution in the diagnosis of an idiopathic disorder
H.J.
Stein
, T.R.
DeMeester
, R.R.
Klingman
(Omaha)
Primary Motility Disorders of the Esophagus
/
Diffuse esophageal spasms (Corkscrew esophagus)
Pain, often pseudoanginal, may be the only symptom
H.J.
Stein
, T.R.
DeMeester
(Omaha)
Primary Motility Disorders of the Esophagus
/
Diffuse esophageal spasms (Corkscrew esophagus)
What is the extent of esophageal body involvement in diffuse esophageal spasm ?
H.J.
Stein
, T.R.
DeMeester
, R.R.
Klingman
(Omaha)
Primary Motility Disorders of the Esophagus
/
Diffuse esophageal spasms (Corkscrew esophagus)
Is the distinction between DES and achalasia not sometimes arbitrary ?
H.J.
Stein
, T.R.
DeMeester
(Omaha)
Primary Motility Disorders of the Esophagus
/
Diffuse esophageal spasms (Corkscrew esophagus)
Is the failure of the LES to relax, or the presence of secondary peristaltic waves, indicative of a poor prognosis after surgery ?
H.J.
Stein
, T.R.
DeMeester
(Omaha)
Primary Motility Disorders of the Esophagus
/
Treatments of diffuse esophageal spasms
What is the success rate with surgical therapy ?
H.J.
Stein
, T.R.
DeMeester
(Omaha)
Primary Motility Disorders of the Esophagus
/
Treatments of diffuse esophageal spasms
Is a good clinical result satisfactory if there is no equivalent manometric improvement ?
H.J.
Stein
, T.R.
DeMeester
(Omaha)
Primary Motility Disorders of the Esophagus
/
Treatments of diffuse esophageal spasms
Can the defective function of the esophagus in diffuse esophageal spasm be improved by esophageal myotomy ?
H.J.
Stein
, T.R.
DeMeester
(Omaha)
Primary Motility Disorders of the Esophagus
/
Idiopathic motor disorders of the esophagus in the elderly
Should myotomy of the crico-pharyngeus be considered when the pharyngeal pressures are near-normal ?
H.J.
Stein
, T.R.
DeMeester
(Omaha)
The Esophagogastric Junction
/
Anatomy-physiology
What is the relationship between muscular structures and the manometric 3-D image of the lower esophageal sphincter?
H.J.
Stein
, O.
Korn
, D.
Liebermann-Meffert
(Munich)
The Esophagogastric Junction
/
Pressure measurements
What is the role of three-dimensional manometric imaging of the lower esophageal sphincter?
H.J.
Stein
, O.
Korn
(Munich)
The Esophagogastric Junction
/
GER and gastric motility factors
What is the respective correlation between light absorption on Bilitec monitoring and bilirubin/bile acid concentration?
H.J.
Stein
, F.
Stipa
, D.
Liebermann-Meffert
(Munich)
The Esophagogastric Junction
/
Esophageal columnar metaplasia (Barrett s esophagus)
What are the indications for antireflux surgery in Barrett's esophagus?
H.J.
Stein
, J.R.
Siewert
(Munich)
Barrett's Esophagus
/
Pathophysiology
Are there specific abnormalities in esophageal function existing in Barrett's patients?
H.J.
Stein
, W.K.H.
Kauer
, J.R.
Siewert
(München)
Barrett's Esophagus
/
Treatments
Should highly selective vagotomy be added to antireflux surgery?
H.J.
Stein
, W.K.H.
Kauer
, J.R.
Siewert
(Munich)
The Esophageal Mucosa
/
Alkaline duodenogastric reflux
What factors contribute to alkaline reflux and why?
S.J.M.
Kraemer
, H.J.
Stein
, H.
Feussner
, J.R.
Siewert
(Munich)
The Esophageal Mucosa
/
Therapeutic strategy
Should the inadequate effects of antisecretory treatment be related to persistence of the aggressive action of alkaline secretions?
H.
Feussner
, H.J.
Stein
, J.R.
Siewert
(Munich)
The Esophageal Mucosa
/
Follow-up
Is 24-h pH measurement adequate to assess these patients?
T.R.
DeMeester
, P.
Burdiles
, H.J.
Stein
, S.E.A.
Attwood
(Los Angeles)
Primary Motility Disorders of the Esophagus
/
Achalasia (hypomotility) is the best known entity
Is the proximal segment of the esophagus often involved in this disorder ?
R.R.
Klingman
, H.J.
Stein
, T.R.
De Meester
(Omaha)
The Esophagogastric Junction
/
GER and gastric motility factors
Is direct intra-esophageal aspiration over an entire circadian cycle the most accurate means of detecting bile acids and pancreatic enzymes in the esophagus?
W.K.H.
Kauer
, H.J.
Stein
(Munich)
The Esophagogastric Junction
/
Particular problems in medical therapy
What is the mechanism of accentuation of the noxious effect of bile acids by acid suppression therapy?
D.
Liebermann-Meffert
, H.J.
Stein
(Munich)
The Esophagogastric Junction
/
Surgical treatments
What attitude should be adopted in failed antireflux procedures?
J.R.
Siewert
, H.J.
Stein
(Munich)
The Esophagogastric Junction
/
Achalasia
What precisions concerning the site and length of myotomy could be expected from the present knowledge on the muscular structure of the lower esophageal sphincter?
D.
Liebermann-Meffert
, H.J.
Stein
(Munich)
Barrett's Esophagus
/
Pathophysiology
What is the prevalence of alkaline material in Barrett's patients?
W.K.H.
Kauer
, H.J.
Stein
, J.R.
Siewert
(Munich)
Barrett's Esophagus
/
Pathophysiology
Is there a correlation between the detrimental effects of bile reflux and the value of the pH in the refluxate?
W.K.H.
Kauer
, H.J.
Stein
, J.R.
Siewert
(Munich)
Barrett's Esophagus
/
Treatments
Are mechanical complications higher after laparoscopic Nissen than after the open approach?
W.K.H.
Kauer
, H.J.
Stein
, J.R.
Siewert
(Munich)
Barrett's Esophagus
/
Adenocarcinomas
Are the data obtained from ambulatory 24-hour fiberoptic monitoring of bilirubin reliable enough to support the role of bile reflux in degeneration of Barrett's mucosa?
W.K.H.
Kauer
, H.J.
Stein
, J.R.
Siewert
(Munich)