Primary Motility  Disorders of the  Esophagus
 The Esophageal
 Mucosa
 The
 Esophagogastric  Junction
 Barrett's
 Esophagus

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H.J. Stein

The Esophageal Mucosa / Strategy of investigations

What may be expected from the new manometric techniques based on the three-dimensional sphincter pressure profile?
H.J. Stein (Munich)

The Esophageal Mucosa / Indications for surgery

Are motility disturbances secondary to reflux and can improvement be anticipated after effective treatment?
H.J. Stein (Munich), T.R. DeMeester (Los Angeles)

The Esophageal Mucosa / Nissen fundoplication

Do we know why only certain antireflux valves come undone?
H.J. Stein, J.R. Siewert (Munich)

The Esophageal Mucosa / Nissen fundoplication

The endoscopy should be performed by the surgeon, especially in recurrences
H.J. Stein, J.R. Siewert, H.J. Dittler (Munich)

The Esophageal Mucosa / Nissen fundoplication

What are the causes of failure of Nissen's operation?
H.J. Stein, J.R. Siewert, H. Feussner (Munich)

The Esophageal Mucosa / Physiopathology

Does esophageal dysfunction in CLE influence bolus propulsion through the esophagus? Does it differ from that of reflux esophagitis?
H.J. Stein (Munich), T.R. DeMeester (Los Angeles)

Primary Motility Disorders of the Esophagus / Diffuse esophageal spasms (Corkscrew esophagus)

The numerous causes which may give rise to DES call for caution in the diagnosis of an idiopathic disorder
H.J. Stein, T.R. DeMeester, R.R. Klingman (Omaha)

Primary Motility Disorders of the Esophagus / Diffuse esophageal spasms (Corkscrew esophagus)

Pain, often pseudoanginal, may be the only symptom
H.J. Stein, T.R. DeMeester (Omaha)

Primary Motility Disorders of the Esophagus / Diffuse esophageal spasms (Corkscrew esophagus)

What is the extent of esophageal body involvement in diffuse esophageal spasm ?
H.J. Stein, T.R. DeMeester, R.R. Klingman (Omaha)

Primary Motility Disorders of the Esophagus / Diffuse esophageal spasms (Corkscrew esophagus)

Is the distinction between DES and achalasia not sometimes arbitrary ?
H.J. Stein, T.R. DeMeester (Omaha)

Primary Motility Disorders of the Esophagus / Diffuse esophageal spasms (Corkscrew esophagus)

Is the failure of the LES to relax, or the presence of secondary peristaltic waves, indicative of a poor prognosis after surgery ?
H.J. Stein, T.R. DeMeester (Omaha)

Primary Motility Disorders of the Esophagus / Treatments of diffuse esophageal spasms

What is the success rate with surgical therapy ?
H.J. Stein, T.R. DeMeester (Omaha)

Primary Motility Disorders of the Esophagus / Treatments of diffuse esophageal spasms

Is a good clinical result satisfactory if there is no equivalent manometric improvement ?
H.J. Stein, T.R. DeMeester (Omaha)

Primary Motility Disorders of the Esophagus / Treatments of diffuse esophageal spasms

Can the defective function of the esophagus in diffuse esophageal spasm be improved by esophageal myotomy ?
H.J. Stein, T.R. DeMeester (Omaha)

Primary Motility Disorders of the Esophagus / Idiopathic motor disorders of the esophagus in the elderly

Should myotomy of the crico-pharyngeus be considered when the pharyngeal pressures are near-normal ?
H.J. Stein, T.R. DeMeester (Omaha)

The Esophagogastric Junction / Anatomy-physiology

What is the relationship between muscular structures and the manometric 3-D image of the lower esophageal sphincter?
H.J. Stein, O. Korn, D. Liebermann-Meffert (Munich)

The Esophagogastric Junction / Pressure measurements

What is the role of three-dimensional manometric imaging of the lower esophageal sphincter?
H.J. Stein, O. Korn (Munich)

The Esophagogastric Junction / GER and gastric motility factors

What is the respective correlation between light absorption on Bilitec monitoring and bilirubin/bile acid concentration?
H.J. Stein, F. Stipa, D. Liebermann-Meffert (Munich)

The Esophagogastric Junction / Esophageal columnar metaplasia (Barrett s esophagus)

What are the indications for antireflux surgery in Barrett's esophagus?
H.J. Stein, J.R. Siewert (Munich)

Barrett's Esophagus / Pathophysiology

Are there specific abnormalities in esophageal function existing in Barrett's patients?
H.J. Stein, W.K.H. Kauer, J.R. Siewert (München)

Barrett's Esophagus / Treatments

Should highly selective vagotomy be added to antireflux surgery?
H.J. Stein, W.K.H. Kauer, J.R. Siewert (Munich)


The Esophageal Mucosa / Alkaline duodenogastric reflux

What factors contribute to alkaline reflux and why?
S.J.M. Kraemer, H.J. Stein, H. Feussner, J.R. Siewert (Munich)

The Esophageal Mucosa / Therapeutic strategy

Should the inadequate effects of antisecretory treatment be related to persistence of the aggressive action of alkaline secretions?
H. Feussner, H.J. Stein, J.R. Siewert (Munich)

The Esophageal Mucosa / Follow-up

Is 24-h pH measurement adequate to assess these patients?
T.R. DeMeester, P. Burdiles, H.J. Stein, S.E.A. Attwood (Los Angeles)

Primary Motility Disorders of the Esophagus / Achalasia (hypomotility) is the best known entity

Is the proximal segment of the esophagus often involved in this disorder ?
R.R. Klingman, H.J. Stein, T.R. De Meester (Omaha)

The Esophagogastric Junction / GER and gastric motility factors

Is direct intra-esophageal aspiration over an entire circadian cycle the most accurate means of detecting bile acids and pancreatic enzymes in the esophagus?
W.K.H. Kauer, H.J. Stein (Munich)

The Esophagogastric Junction / Particular problems in medical therapy

What is the mechanism of accentuation of the noxious effect of bile acids by acid suppression therapy?
D. Liebermann-Meffert, H.J. Stein (Munich)

The Esophagogastric Junction / Surgical treatments

What attitude should be adopted in failed antireflux procedures?
J.R. Siewert, H.J. Stein (Munich)

The Esophagogastric Junction / Achalasia

What precisions concerning the site and length of myotomy could be expected from the present knowledge on the muscular structure of the lower esophageal sphincter?
D. Liebermann-Meffert, H.J. Stein (Munich)

Barrett's Esophagus / Pathophysiology

What is the prevalence of alkaline material in Barrett's patients?
W.K.H. Kauer, H.J. Stein, J.R. Siewert (Munich)

Barrett's Esophagus / Pathophysiology

Is there a correlation between the detrimental effects of bile reflux and the value of the pH in the refluxate?
W.K.H. Kauer, H.J. Stein, J.R. Siewert (Munich)

Barrett's Esophagus / Treatments

Are mechanical complications higher after laparoscopic Nissen than after the open approach?
W.K.H. Kauer, H.J. Stein, J.R. Siewert (Munich)

Barrett's Esophagus / Adenocarcinomas

Are the data obtained from ambulatory 24-hour fiberoptic monitoring of bilirubin reliable enough to support the role of bile reflux in degeneration of Barrett's mucosa?
W.K.H. Kauer, H.J. Stein, J.R. Siewert (Munich)