Primary Motility  Disorders of the  Esophagus
 The Esophageal
 Mucosa
 The
 Esophagogastric  Junction
 Barrett's
 Esophagus

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J.E. Richter

The Esophageal Mucosa / Strategy of investigations

Is it possible to define the abnormal parameters of pH measurement in elderly subjects?
J.E. Richter (Birmingham, Alabama)

The Esophageal Mucosa / Stenoses

What type of mild stenoses may reverse with medical therapy only, without dilatation?
J.E. Richter (Birmingham, Alabama)

The Esophageal Mucosa / Therapeutic strategy

What are the goals of treatment in reflux esophagitis?
J.E. Richter (Birmingham, Alabama)

The Esophageal Mucosa / Indications for surgery

Two examinations seem indispensable: - pH measurement to confirm doubtful diagnoses - manometry for choice of technique
J.E. Richter (Birmingham, Alabama)

Primary Motility Disorders of the Esophagus / Manometric observations in the normal subject

What is the incidence of double peaks in peristaltic waves ?
J.E. Richter (Birmingham), W.J. Dodds (Milwaukee)

Primary Motility Disorders of the Esophagus / Manometric observations in the normal subject

How accurate are water-filled infusion systems in measuring pharyngeal motor function ?
J.E. Richter (Birmingham), W.J. Dodds (Milwaukee)

Primary Motility Disorders of the Esophagus / Achalasia (hypomotility) is the best known entity

Can cases where relaxation is preserved be considered as initial stages ?
J.E. Richter (Birmingham)

Primary Motility Disorders of the Esophagus / Achalasia (hypomotility) is the best known entity

What is the duration of relaxation in these cases ?
J.E. Richter (Birmingham)

Primary Motility Disorders of the Esophagus / Painful esophageal peristalsis (nutcracker esophagus)

Is the natural history of the nutcracker esophagus known ?
J.E. Richter (Birmingham)

Primary Motility Disorders of the Esophagus / Painful esophageal peristalsis (nutcracker esophagus)

Do the clinic aspects of nutcracker esophagus parallel the features of the irritable bowel syndrome ?
J.E. Richter (Birmingham)

Primary Motility Disorders of the Esophagus / Painful esophageal peristalsis (nutcracker esophagus)

Are not the abnormalities existing in the distal esophagus during radionuclide transit due to intermittent gastroesophageal reflux ?
J.E. Richter (Birmingham)

Primary Motility Disorders of the Esophagus / Painful esophageal peristalsis (nutcracker esophagus)

Is the nutcracker esophagus primarily a manometric diagnosis ?
J.E. Richter (Birmingham)

Primary Motility Disorders of the Esophagus / Painful esophageal peristalsis (nutcracker esophagus)

What is the correlation between esophageal scintigraphy and manometry ?
J.E. Richter (Birmingham)

Primary Motility Disorders of the Esophagus / Painful esophageal peristalsis (nutcracker esophagus)

Is the esophageal clearance always normal in nutcracker esophagus ?
J.E. Richter (Birmingham)

Primary Motility Disorders of the Esophagus / Painful esophageal peristalsis (nutcracker esophagus)

As in the irritable bowel syndrome, may emotional factors modify pain perception in the nutcracker esophagus ? Should these patients be given psychotropic treatments ?
J.E. Richter (Birmingham)

Primary Motility Disorders of the Esophagus / Nonspecific anomalies

May psychological and environmental stressors have an effect on peristaltic esophageal contractions ?
J.E. Richter (Birmingham)

Primary Motility Disorders of the Esophagus / Pseudoanginal pains of esophageal origin

What part is played by esophageal distention without pharmacologic provocation ?
J.E. Richter (Birmingham)

The Esophagogastric Junction / pH-measurements

What is the reproducibility of 24-hour recording of esophageal pH?
J.E. Richter (Cleveland)

The Esophagogastric Junction / ph-manometry

What are the indications for 24-hour ambulatory pH and manometry measurement?
J.E. Richter (Cleveland)

The Esophagogastric Junction / GER and gastric motility factors

Is bilirubin measurement accurate in an acid environment?
J.E. Richter (Cleveland)

The Esophagogastric Junction / GER and gastric motility factors

What is the temporal relationship existing between a rising gastric pH and esophageal pH >= 7?
J.E. Richter (Cleveland)

The Esophagogastric Junction / GER and gastric motility factors

Should the term "alkaline reflux" continue to be used?
J.E. Richter (Cleveland)

Barrett's Esophagus / Diagnosis

What is the histological correlation with clinical and endoscopic evidence of Barrett's esophagus?
J.E. Richter (Cleveland)

Barrett's Esophagus / Short Barrett's esophagus

Is "minimal" or ultra-short segment Barrett's esophagus a consistent reality?
J.E. Richter (Cleveland)

Barrett's Esophagus / Pathophysiology

What is the relationship between bile and alkaline reflux?
J.E. Richter (Cleveland)

Barrett's Esophagus / Dysplasia

What is the long-term significance of low-grade dysplasia?
J.E. Richter (Cleveland)

Barrett's Esophagus / Treatments

Can promotility agents maintain remission in Barrett's esophagus?
J.E. Richter (Cleveland)


Primary Motility Disorders of the Esophagus / Manometric observations in the normal subject

What are the normal peak values for esophageal contractions ?
W.J. Dodds (Milwaukee), J.E. Richter (Birmingham)

Primary Motility Disorders of the Esophagus / Achalasia (hypomotility) is the best known entity

Does the persistence of an LES high-pressure zone prevent reflux after a Heller myotomy ?
W.J. Dodds (Milwaukee), J.E. Richter (Birmingham)

Primary Motility Disorders of the Esophagus / Painful esophageal peristalsis (nutcracker esophagus)

What is the explanation for the lack of correlation between the amplitude and duration of repetitive contractions and the rate of fluid transport ?
W.J. Dodds (Milwaukee), J.E. Richter (Birmingham)