Primary Motility Disorders of the Esophagus
The Esophageal
Mucosa
The
Esophagogastric Junction
Barrett's
Esophagus
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J.E. Richter
The Esophageal Mucosa
/
Strategy of investigations
Is it possible to define the abnormal parameters of pH measurement in elderly subjects?
J.E.
Richter
(Birmingham, Alabama)
The Esophageal Mucosa
/
Stenoses
What type of mild stenoses may reverse with medical therapy only, without dilatation?
J.E.
Richter
(Birmingham, Alabama)
The Esophageal Mucosa
/
Therapeutic strategy
What are the goals of treatment in reflux esophagitis?
J.E.
Richter
(Birmingham, Alabama)
The Esophageal Mucosa
/
Indications for surgery
Two examinations seem indispensable: - pH measurement to confirm doubtful diagnoses - manometry for choice of technique
J.E.
Richter
(Birmingham, Alabama)
Primary Motility Disorders of the Esophagus
/
Manometric observations in the normal subject
What is the incidence of double peaks in peristaltic waves ?
J.E.
Richter
(Birmingham), W.J.
Dodds
(Milwaukee)
Primary Motility Disorders of the Esophagus
/
Manometric observations in the normal subject
How accurate are water-filled infusion systems in measuring pharyngeal motor function ?
J.E.
Richter
(Birmingham), W.J.
Dodds
(Milwaukee)
Primary Motility Disorders of the Esophagus
/
Achalasia (hypomotility) is the best known entity
Can cases where relaxation is preserved be considered as initial stages ?
J.E.
Richter
(Birmingham)
Primary Motility Disorders of the Esophagus
/
Achalasia (hypomotility) is the best known entity
What is the duration of relaxation in these cases ?
J.E.
Richter
(Birmingham)
Primary Motility Disorders of the Esophagus
/
Painful esophageal peristalsis (nutcracker esophagus)
Is the natural history of the nutcracker esophagus known ?
J.E.
Richter
(Birmingham)
Primary Motility Disorders of the Esophagus
/
Painful esophageal peristalsis (nutcracker esophagus)
Do the clinic aspects of nutcracker esophagus parallel the features of the irritable bowel syndrome ?
J.E.
Richter
(Birmingham)
Primary Motility Disorders of the Esophagus
/
Painful esophageal peristalsis (nutcracker esophagus)
Are not the abnormalities existing in the distal esophagus during radionuclide transit due to intermittent gastroesophageal reflux ?
J.E.
Richter
(Birmingham)
Primary Motility Disorders of the Esophagus
/
Painful esophageal peristalsis (nutcracker esophagus)
Is the nutcracker esophagus primarily a manometric diagnosis ?
J.E.
Richter
(Birmingham)
Primary Motility Disorders of the Esophagus
/
Painful esophageal peristalsis (nutcracker esophagus)
What is the correlation between esophageal scintigraphy and manometry ?
J.E.
Richter
(Birmingham)
Primary Motility Disorders of the Esophagus
/
Painful esophageal peristalsis (nutcracker esophagus)
Is the esophageal clearance always normal in nutcracker esophagus ?
J.E.
Richter
(Birmingham)
Primary Motility Disorders of the Esophagus
/
Painful esophageal peristalsis (nutcracker esophagus)
As in the irritable bowel syndrome, may emotional factors modify pain perception in the nutcracker esophagus ? Should these patients be given psychotropic treatments ?
J.E.
Richter
(Birmingham)
Primary Motility Disorders of the Esophagus
/
Nonspecific anomalies
May psychological and environmental stressors have an effect on peristaltic esophageal contractions ?
J.E.
Richter
(Birmingham)
Primary Motility Disorders of the Esophagus
/
Pseudoanginal pains of esophageal origin
What part is played by esophageal distention without pharmacologic provocation ?
J.E.
Richter
(Birmingham)
The Esophagogastric Junction
/
pH-measurements
What is the reproducibility of 24-hour recording of esophageal pH?
J.E.
Richter
(Cleveland)
The Esophagogastric Junction
/
ph-manometry
What are the indications for 24-hour ambulatory pH and manometry measurement?
J.E.
Richter
(Cleveland)
The Esophagogastric Junction
/
GER and gastric motility factors
Is bilirubin measurement accurate in an acid environment?
J.E.
Richter
(Cleveland)
The Esophagogastric Junction
/
GER and gastric motility factors
What is the temporal relationship existing between a rising gastric pH and esophageal pH >= 7?
J.E.
Richter
(Cleveland)
The Esophagogastric Junction
/
GER and gastric motility factors
Should the term "alkaline reflux" continue to be used?
J.E.
Richter
(Cleveland)
Barrett's Esophagus
/
Diagnosis
What is the histological correlation with clinical and endoscopic evidence of Barrett's esophagus?
J.E.
Richter
(Cleveland)
Barrett's Esophagus
/
Short Barrett's esophagus
Is "minimal" or ultra-short segment Barrett's esophagus a consistent reality?
J.E.
Richter
(Cleveland)
Barrett's Esophagus
/
Pathophysiology
What is the relationship between bile and alkaline reflux?
J.E.
Richter
(Cleveland)
Barrett's Esophagus
/
Dysplasia
What is the long-term significance of low-grade dysplasia?
J.E.
Richter
(Cleveland)
Barrett's Esophagus
/
Treatments
Can promotility agents maintain remission in Barrett's esophagus?
J.E.
Richter
(Cleveland)
Primary Motility Disorders of the Esophagus
/
Manometric observations in the normal subject
What are the normal peak values for esophageal contractions ?
W.J.
Dodds
(Milwaukee), J.E.
Richter
(Birmingham)
Primary Motility Disorders of the Esophagus
/
Achalasia (hypomotility) is the best known entity
Does the persistence of an LES high-pressure zone prevent reflux after a Heller myotomy ?
W.J.
Dodds
(Milwaukee), J.E.
Richter
(Birmingham)
Primary Motility Disorders of the Esophagus
/
Painful esophageal peristalsis (nutcracker esophagus)
What is the explanation for the lack of correlation between the amplitude and duration of repetitive contractions and the rate of fluid transport ?
W.J.
Dodds
(Milwaukee), J.E.
Richter
(Birmingham)