R.W. McCallum

The Esophageal Mucosa / Long-term treatments May bacterial treatment directed against Helicobacter pylori have an effect on relapse in the small group of antritis due to H. pylori combined with reflux? R.W. McCallum, J. Sarosiek (Charlottesville)

The Esophageal Mucosa / Physiopathology Should the use of pharmacologic agents promoting gastric emptying be reconsidered? R.W. McCallum (Charlottesville)

The Esophageal Mucosa / The dysplastic mucosa How can one define a subpopulation most at risk of degeneration? R.W. McCallum (Charlottesville)

Primary Motility Disorders of the Esophagus / Physiology Is it now established that the LES and stomach have opiate receptors ? R.W. McCallum (Charlottesville)

Primary Motility Disorders of the Esophagus / Achalasia (hypomotility) is the best known entity Is there any correlation between the rest-pressure of the LES and the stage of esophageal emptying as shown by scintigraphy ? R.W. McCallum (Charlottesville)

Primary Motility Disorders of the Esophagus / Achalasia (hypomotility) is the best known entity Nifedipine lowers LES pressure in the same way as in normal subjects R.W. McCallum (Charlottesville)

Primary Motility Disorders of the Esophagus / Achalasia (hypomotility) is the best known entity What is the role of repair of the crura to restore sphincter function ? R.W. McCallum (Charlottesville)

Primary Motility Disorders of the Esophagus / Achalasia (hypomotility) is the best known entity The subjective response to either treatment is related to the percent change in LESP and not the basal LESP or the absolute change in the LESP R.W. McCallum (Charlottesville)

Primary Motility Disorders of the Esophagus / Treatments of diffuse esophageal spasms Unlike the findings in achalasia, nifedipine decreases LESP and contraction amplitude to a greater extent than in normal subjects R.W. McCallum (Charlottesville)

Primary Motility Disorders of the Esophagus / Painful esophageal peristalsis (nutcracker esophagus) Is peristalsis always normal ? R.W. McCallum (Charlottesville)

Primary Motility Disorders of the Esophagus / Painful esophageal peristalsis (nutcracker esophagus) What is the frequency of peristaltic waves compared to DES ? R.W. McCallum (Charlottesville)

Primary Motility Disorders of the Esophagus / Painful esophageal peristalsis (nutcracker esophagus) Nitroderivatives R.W. McCallum (Charlottesville)

Primary Motility Disorders of the Esophagus / Transitional forms Those between the nutcracker esophagus and diffuse esophageal spasm seem equally well known R.W. McCallum (Charlottesville)

Primary Motility Disorders of the Esophagus / Nonspecific anomalies The hypertensive LES has quite special features R.W. McCallum (Charlottesville)

Primary Motility Disorders of the Esophagus / Nonspecific anomalies Spasms localized to the lower part of the esophagus are a new entity R.W. McCallum (Charlottesville)

Primary Motility Disorders of the Esophagus / Pseudoanginal pains of esophageal origin How does one distinguish the cardiac and esophageal efficacy of the therapeutic agents ? R.W. McCallum (Charlottesville)

The Esophagogastric Junction / GER and gastric motility factors What is the value of electrogastrography in reflux disease? R.W. McCallum, I. Soykan (Kansas City)

The Esophagogastric Junction / Lower esophageal mucosal rings What is the information given by esophageal manometry in patients with lower esophageal rings? R.W. McCallum, I. Soykan (Kansas City)

The Esophageal Mucosa / Mucosal protective agents What part do the mucous cells of submucosal mucous glands play in the esophageal pre-epithelial barrier? J. Sarosiek, Z. Namiot, R. Piasclk, D.P. Hetzel, RM. Rourk, M.C. Edmunds, T.M. Daniel, R.W. McCallum (Charlottesville)

The Esophagogastric Junction / GER and barrier dysfunction Is pepsin concentration related to the amount or duration of acid exposure? - How can the delayed acid clearance observed in gastroesophageal reflux disease patients with hiatal hernia be interpreted? R.L. Brown, J. Sarosiek, R.W. McCallum (Kansas City)

The Esophagogastric Junction / GER and gastric motility factors What is the effect of cholecystokinin A antagonists (loxiglumide) on solid and liquid gastric emptying? R.L. Brown, J. Sarosiek, R.W. McCallum (Kansas City)

The Esophagogastric Junction / EGJ and GER disease Why is reflux esophagitis a predominantly male disease? J. Sarosiek, R.W. McCallum (Kansas City)

The Esophagogastric Junction / EGJ and GER disease What is the role of salivary and esophageal prostaglandin E2 in esophageal protection? J. Sarosiek, M. Marcinkiewicz, T. Zbroch, R.W. McCallum (Kansas City)

The Esophagogastric Junction / Surgical treatments Is there a role for selective vagotomy in addition to antireflux surgery? R.L. Brown, J. Sarosiek, R.W. McCallum (Kansas City)

The Esophagogastric Junction / Esophageal columnar metaplasia (Barrett s esophagus) Is there an explanation for the predominance of Barrett's esophagus and adenocarcinoma in white male patients? J. Sarosiek, R.W. McCallum (Kansas City)

The Esophagogastric Junction / Esophageal columnar metaplasia (Barrett s esophagus) What is the most frequent site of the stenosis? J. Sarosiek, R.W. McCallum (Kansas City)

The Esophagogastric Junction / Esophageal columnar metaplasia (Barrett s esophagus) Could lowering of salivary and esophageal epidermal growth factor in severe reflux esophagitis be related to the development of Barrett's mucosa? M. Marcinkiewicz, J. Sarosiek, R.W. McCallum (Kansas City)