348. How common are anginal syndromes associated with normal coronary arteriography ?
M.C. Aumont, D. Himbert, R. Gourgon (Paris)

349. What proportion of pseudoanginas are due to reflux ?
D.O. Castell (Philadelphia)

350. Are there specific neural structures that might serve the mechanoreceptive and thermoreceptive reflexes that modify esophageal motility ?
J. Christensen (Iowa City)

351. Is the presence of chemoreceptors in the esophageal mucosa proven ?
J. Christensen (Iowa City)

352. Is it likely that other mechanisms exist ?
J. Salducci (Marseilles)

353. What is the role of food intake osmolality in the genesis of chest pain ?
J. M. Suduca, M. Delvaux, J. Frexinos (Toulouse)

354. Can one explain the isolated role of motor disorders in the pain ?
J. M. Suduca, M. Delvaux, J. Frexinos (Toulouse)

355. What part is played by anomalies of the cardiac microcirculation combined with esophageal disorders ?
S.B. Benjamin (Washington)

356. Pyrosis may be provoked by physical exertion
J. Janssens, G. Vantrappen (Leuven)

357. Odynophagia is less of a problem, as there is a clear relation between pain and swallowing
J. Janssens, G. Vantrappen (Leuven)

358. What are the characteristics of angina-like chest pain ?
J-Y. Touchais, Ph. Ducrotte, Ph. Denis (Rouen)

359. Are chest pains of esophageal or cardiac origin different or not ?
J. Y. Touchais, Ph. Ducrotte, Ph. Denis (Rouen)

360. What is the incidence of abdominal reference of esophageal pain ?
O. Bouche, P. Zeitoun (Reims)

361. How to confirm the esophageal origin of the pain ?
J. Y. Touchais, Ph. Ducrotte, Ph. Denis (Rouen)

362. What are the manometric findings observed during the painful crises and at other times ?
G. Cargill (Paris)

363. Is the simultaneous occurrence of esophageal pain and spasm in a patient with a normal heart essential in making the diagnosis of esophageal angina ?
J. Guerre (Paris)

364. Can esophageal motor disorders be responsible for pain ?
J. Y. Touchais, Ph. Ducrotte, Ph. Denis (Rouen)

365. How to classify isolated thoracic pain without manometric anomalies ?
D.O. Castell (Philadelphia)

366. What different modalities are available to provoke motility disorders and chest pain?
B. Dupin (Marseilles)

367. Bethanechol injections
D.O. Castell (Philadelphia)

368. Pentagastrin
M.D. Kaye (Honolulu)

369. Ergometrine is the most effective agent, but the cardiac risks limit its use
B. Dupin (Marseilles)

370. Edrophonium is the most interesting pharmacological agent for the diagnosis but cannot be regarded as physiologic
A. Gosselin, A. Ropert, M. Gosselin (Rennes)

371. What part is played by esophageal distention without pharmacologic provocation ?
J.-E. Richter (Birmingham)

372. How valuable is Bernstein's test ?
D.O. Castell (Philadelphia)

373. How does one distinguish the cardiac and esophageal efficacy of the therapeutic agents ?
R. W. McCallum (Charlottesville)

374. In patients with coronary insufficiency, should not the effects of longterm treatment with nitroderivatives and calcium antagonists be taken into account as a possible cause of GER ?
M. Bortolotti (Bologna)

375. Have prolonged recording of pH and pressure provided evidence of the concordance of pain, motor disorders and possibility of reflux ?
J. Janssens (Leuven)

376. Is Dent's sleeve system preferable for these longterm recordings ?
J. Dent (Adelaide)

377. Is Holter's triple investigation desirable to avoid unnecessary coronary arteriography ?
D. Andresen, Th. Brüggemann, H. Völler, R. Schroder (Berlin)

378. Are the procedures of computer recording reliable ?
J.A. Castell (Philadelphia)

379. Could chest pain seen during lidocaine be due to gastric reflux and poor clearance of reflux material ?
D.O. Castell (Philadelphia)

380. What are the therapeutic implications of the etiologic diagnosis of noncardiac chest pain of esophageal origin ?
R. Jian, M. Lemann (Paris)

381. In many cases, the finding of an esophagitis at endoscopy confirmed by pH measurements may definitively establish the source of these pains
J. Janssens, G. Vantrappen (Leuven)

382. Do normal results of pH measurement allow to exclude the esophageal origin of the chest pain ?
G. Vantrappen (Leuven)