bannerHON
img
HONnews
HONnews
img PATIENT / PARTICULIER img PROFESSIONNEL DE SANTE img WEBMESTRE img
img
 
img
HONcode sites
Khresmoi - new !
HONselect
News
Conferences
Images

Themes:
A B C D E F G H I
J K L M N O P Q
R S T U V W X Y Z
Browse archive:
2019: S A J J M A M F J
2018: D N O S

 
  Other news for:
Alcoholism
Genetics
 Resources from HONselect
How Heavy Drinking Might Boost Your Appetite for Alcohol

By Robert Preidt

MONDAY, Feb. 11, 2019 (HealthDay News) -- Binge and heavy drinking may trigger DNA changes that make your booze cravings worse, a new study says.

"We found that people who drink heavily may be changing their DNA in a way that makes them crave alcohol even more," said senior study author Dipak Sarkar. He directs the endocrine program in the School of Environmental and Biological Sciences at Rutgers University in New Brunswick, N.J.

Sarkar and his team focused on two genes that play a role in controlling drinking: PER2, which influences the body's biological clock, and POMC, which regulates the stress-response system.

The researchers found that in binge and heavy drinkers, the two genes had changes caused by an alcohol-influenced gene modification process called methylation.

The binge and heavy drinkers also had reductions in gene expression, which is the rate at which the two genes create proteins.

These changes in the two genes increased with alcohol intake, according to the study.

The researchers also found that the alcohol-triggered changes in the two genes of binge and heavy drinkers were associated with a greater craving for alcohol.

"This may help explain why alcoholism is such a powerful addiction, and may one day contribute to new ways to treat alcoholism or help prevent at-risk people from becoming addicted," Sarkar said in a Rutgers news release.

The findings may also help researchers identify proteins or genes that could predict a person's risk for binge or heavy drinking," Sarkar added.

There were more than 3 million alcohol-related deaths worldwide in 2016, which was 5 percent of all deaths globally, according to the World Health Organization. Harmful use of alcohol was also linked with about 5 percent of disease and injuries worldwide.

The study was published recently in the journal Alcoholism: Clinical & Experimental Research.

More information

The U.S. National Institute on Alcohol Abuse and Alcoholism has more on alcohol and your health.

SOURCE: Rutgers University, news release, Jan. 29, 2019

Copyright © 2019 HealthDay. All rights reserved. URL:http://consumer.healthday.com/Article.asp?AID=742140

Resources from HONselect: HONselect is the HON's medical search engine. It retrieves scientific articles, images, conferences and web sites on the selected subject.
Alcoholism
Appetite
Research Personnel
DNA
Proteins
Wounds and Injuries
The list of medical terms above are retrieved automatically from the article.

Disclaimer: The text presented on this page is not a substitute for professional medical advice. It is for your information only and may not represent your true individual medical situation. Do not hesitate to consult your healthcare provider if you have any questions or concerns. Do not use this information to diagnose or treat a health problem or disease without consulting a qualified healthcare professional.
Be advised that HealthDay articles are derived from various sources and may not reflect your own country regulations. The Health On the Net Foundation does not endorse opinions, products, or services that may appear in HealthDay articles.


Home img About us img MediaCorner img HON newsletter img Site map img Ethical policies img Contact