bannerHON
img
HONnews
HONnews
img PATIENT / PARTICULIER img PROFESSIONNEL DE SANTE img WEBMESTRE img
img
 
img
HONcode sites
Khresmoi - new !
HONselect
News
Conferences
Images

Themes:
A B C D E F G H I
J K L M N O P Q
R S T U V W X Y Z
Browse archive:
2017: D N O S A J J M A M F J
2016: D

 
  Other news for:
Breast Neoplasms
 Resources from HONselect
Nerlynx Approved to Help Prevent Breast Cancer's Return
Drug is designed to block cancer-fueling enzymes

By Scott Roberts

TUESDAY, July 18, 2017 (HealthDay News) -- Nerlynx (neratinib) has been approved by the U.S. Food and Drug Administration to help prevent HER2-positive breast cancer from returning.

It's the first drug designed to prevent return of HER2-positive breast cancer, a genetic form of the disease that's particularly aggressive and can spread to other parts of the body, the agency said in a news release.

The drug is meant for what's known as extended adjuvant therapy -- given after initial treatment, to further reduce the risk that cancer will return.

Breast cancer is the most common form of cancer in the United States, the FDA said. The disease is projected to be diagnosed in more than 250,000 women this year, and more than 46,000 are likely to die of the disease, according to the U.S. National Cancer Institute.

Nerlynx, among a class of drugs designed to block enzymes that fuel cancer-cell growth, was evaluated in clinical studies involving more than 2,800 people with early-stage HER2-positive breast cancer who had completed treatment with the chemotherapy drug trastuzumab. After two years, 94.2 percent of users hadn't had their cancer recur, compared with 91.9 percent of those treated with an inactive placebo.

The most common side effects of Nerlynx included diarrhea, nausea, abdominal pain, fatigue, vomiting, rash and mouth swelling. People who take the drug should be given the anti-diarrhea medication loperamide for the first 50 days of use, the FDA advised.

Women who are pregnant shouldn't take Nerlynx because it can harm a developing fetus, the agency added.

Approval for Nerlynx was granted to Puma Biotechnology, based in Los Angeles.

More information

Visit the FDA to learn more.

SOURCE: July 17, 2017, news release, U.S. Food and Drug Administration

Copyright © 2017 HealthDay. All rights reserved. URL:http://consumer.healthday.com/Article.asp?AID=724701

Resources from HONselect: HONselect is the HON's medical search engine. It retrieves scientific articles, images, conferences and web sites on the selected subject.
Neoplasms
Breast
Breast Neoplasms
Therapeutics
Women
The list of medical terms above are retrieved automatically from the article.

Disclaimer: The text presented on this page is not a substitute for professional medical advice. It is for your information only and may not represent your true individual medical situation. Do not hesitate to consult your healthcare provider if you have any questions or concerns. Do not use this information to diagnose or treat a health problem or disease without consulting a qualified healthcare professional.
Be advised that HealthDay articles are derived from various sources and may not reflect your own country regulations. The Health On the Net Foundation does not endorse opinions, products, or services that may appear in HealthDay articles.


Inicio img Sobre nosotros img Rincón de la prensa img Boletín HON img Mapa del sitio img Política ética img Contactos