bannerHON
img
HONnews
HONnews
img PATIENT / PARTICULIER img PROFESSIONNEL DE SANTE img WEBMESTRE img
img
 
img
HONcode sites
Khresmoi - new !
HONselect
News
Conferences
Images

Themes:
A B C D E F G H I
J K L M N O P Q
R S T U V W X Y Z
Browse archive:
2017: O S A J J M A M F J
2016: D N O

 
  Other news for:
Diarrhea
 Resources from HONselect
Xermelo Approved for Tumor-Related Diarrhea
Drug will treat a condition called carcinoid syndrome diarrhea

By Scott Roberts

WEDNESDAY, March 1, 2017 (HealthDay News) -- Xermelo (telotristat ethyl) tablets have been approved by the U.S. Food and Drug Administration to treat adults with carcinoid syndrome diarrhea, one of a collection of symptoms related to rare carcinoid tumors.

Most of these slow-growing tumors are found in the gastrointestinal tract, the agency said in a news release. Carcinoid syndrome occurs in fewer than 10 percent of people with carcinoid tumors, commonly after the tumor has spread to the liver. The tumor releases an excess amount of the hormone serotonin, leading to diarrhea.

Complications can include weight loss, malnutrition, dehydration and an imbalance of electrolytes.

Xermelo, taken three times daily with food, is designed to inhibit production of serotonin by carcinoid tumors, the FDA said.

The drug was evaluated in clinical studies involving 90 adults with carcinoid syndrome diarrhea, comparing results from those treated with the drug versus a placebo. The agency warned that people given a higher-than-recommended dose developed severe constipation, and one required hospitalization. Any Xermelo user who develops severe constipation or abdominal pain should stop the drug and contact a doctor, the FDA said.

Xermelo is produced by Lexicon Pharmaceuticals, based in Woodlands, Texas.

More information

Visit the FDA to to learn more.

Copyright © 2017 HealthDay. All rights reserved. URL:http://consumer.healthday.com/Article.asp?AID=720232

Resources from HONselect: HONselect is the HON's medical search engine. It retrieves scientific articles, images, conferences and web sites on the selected subject.
Diarrhea
Carcinoid Tumor
Neoplasms
Syndrome
Adult
Constipation
Serotonin
Electrolytes
The list of medical terms above are retrieved automatically from the article.

Disclaimer: The text presented on this page is not a substitute for professional medical advice. It is for your information only and may not represent your true individual medical situation. Do not hesitate to consult your healthcare provider if you have any questions or concerns. Do not use this information to diagnose or treat a health problem or disease without consulting a qualified healthcare professional.
Be advised that HealthDay articles are derived from various sources and may not reflect your own country regulations. The Health On the Net Foundation does not endorse opinions, products, or services that may appear in HealthDay articles.


Home img About us img MediaCorner img HON newsletter img Site map img Ethical policies img Contact