bannerHON
img
HONnews
HONnews
img PATIENT / PARTICULIER img PROFESSIONNEL DE SANTE img WEBMESTRE img
img
 
img
HONcode sites
All Web sites
HONselect
News
Conferences
Images

Themes:
A B C D E F G H I
J K L M N O P Q
R S T U V W X Y Z
Browse archive:
2014: J J M A M F J
2013: D N O S A J

 
  Other news for:
Alzheimer Disease
Genetics
 Resources from HONselect
Gene Variant May Double Alzheimer's Risk for Women: Study
Effect wasn't nearly as pronounced among men, researchers say

By Robert Preidt

MONDAY, April 14, 2014 (HealthDay News) -- Having a copy of a certain gene variant increases women's risk for Alzheimer's disease much more than it does for men, a new study indicates.

Stanford University researchers analyzed data from more than 8,000 people, most older than 60, who were tracked over a long period of time at about 30 Alzheimer's centers across the United States.

Overall, having a copy of the ApoE4 gene variant increased the risk of Alzheimer's. But further analysis showed that women with a copy of this gene variant were about twice as likely to develop Alzheimer's as those who did not have the variant. Men with the ApoE4 variant had only a slightly increased risk of developing Alzheimer's, according to the study in the April 14 issue of the Annals of Neurology.

The findings could help improve understanding of the underlying causes of Alzheimer's disease, according to senior study author Dr. Michael Greicius. He's an assistant professor of neurology and neurological sciences, and medical director of the Stanford Center for Memory Disorders.

Greicius noted that women are much more likely than men to develop Alzheimer's, and that this difference is only partly due to the fact that women tend to live longer than men.

"Even after correcting for age, women appear to be at greater risk," Greicius said in a Stanford news release.

The findings also suggest that doctors need to take different approaches when dealing with women and men.

"These days, a lot of people are getting genotyped [genetic testing] either in the clinic or commercially. People come to me and say, 'I have an ApoE4 gene, what should I do?' If that person is a man, I would tell him that his risk is not increased much if at all. If it's a woman, my advice will be different," Greicius said.

Between 5 million and 6 million Americans have Alzheimer's, and that number could more than double by mid-century, according to experts.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about Alzheimer's disease.

SOURCE: Stanford University, news release, April 14, 2014

Copyright © 2014 HealthDay. All rights reserved. URL:http://consumer.healthday.com/Article.asp?AID=686668

Resources from HONselect: HONselect is the HON's medical search engine. It retrieves scientific articles, images, conferences and web sites on the selected subject.
Women
Risk
Men
Research Personnel
Alzheimer Disease
Memory Disorders
The list of medical terms above are retrieved automatically from the article.

Disclaimer: The text presented on this page is not a substitute for professional medical advice. It is for your information only and may not represent your true individual medical situation. Do not hesitate to consult your healthcare provider if you have any questions or concerns. Do not use this information to diagnose or treat a health problem or disease without consulting a qualified healthcare professional.
Be advised that HealthDay articles are derived from various sources and may not reflect your own country regulations. The Health On the Net Foundation does not endorse opinions, products, or services that may appear in HealthDay articles.


Home img About us img MediaCorner img HON newsletter img Site map img Ethical policies img Contact