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Imbruvica Approval Expanded to Include Chronic Leukemia
Drug inhibits enzyme that spurs cancer growth

By Scott Roberts

WEDNESDAY, Feb. 12, 2014 (HealthDay News) -- U.S. Food and Drug Administration approval of Imbruvica (ibrutinib) has been expanded to include people with chronic lymphocytic leukemia (CLL) who have tried at least one other anti-cancer therapy.

CLL progresses slowly, gradually leading to an increase in white blood cells called B lymphocytes. Last year, some 15,680 Americans were diagnosed with CLL and 4,580 died from it, the agency said Wednesday in a news release, citing the National Cancer Institute.

Imbruvica was approved last November to treat people with mantle cell lymphoma.

Approval for CLL was based on clinical studies involving 48 people, the FDA said. Some 58 percent of participants had their cancer shrink after treatment.

Among the most common side effects of the drug were: low blood platelets, diarrhea, bruising, upper respiratory tract infection, fatigue and muscle pain.

Imbruvica is manufactured by Pharmacyclics, based in Sunnyvale, Calif.

More information

The FDA has more about this approval.

Copyright © 2014 HealthDay. All rights reserved. URL:http://consumer.healthday.com/Article.asp?AID=684846

Resources from HONselect: HONselect is the HON's medical search engine. It retrieves scientific articles, images, conferences and web sites on the selected subject.
Leukemia
Neoplasms
Blood
Blood Platelets
Cells
Infection
Leukemia, Lymphocytic
Muscles
Therapeutics
Lymphocytes
The list of medical terms above are retrieved automatically from the article.

Disclaimer: The text presented on this page is not a substitute for professional medical advice. It is for your information only and may not represent your true individual medical situation. Do not hesitate to consult your healthcare provider if you have any questions or concerns. Do not use this information to diagnose or treat a health problem or disease without consulting a qualified healthcare professional.
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