bannerHON
img
HONnews
HONnews
img PATIENT / PARTICULIER img PROFESSIONNEL DE SANTE img WEBMESTRE img
img
 
img
HONcode sites
All Web sites
HONselect
News
Conferences
Images

Themes:
A B C D E F G H I
J K L M N O P Q
R S T U V W X Y Z
Browse archive:
2014: A J J M A M F J
2013: D N O S A

 
  Other news for:
Emergencies
First Aid
Hospitals
Vitamins
 Resources from HONselect
Giving Magnesium to Stroke Victims Early Not Helpful: Study
Made no difference in long-term outcomes, but other drugs being developed might, study says

By Robert Preidt

FRIDAY, Feb. 14, 2014 (HealthDay News) -- Giving magnesium to stroke patients while they're being taken to the hospital does not reduce the severity of their disabilities three months later, a new study finds.

Paramedics gave magnesium intravenously to 1,700 stroke patients in California to try to protect their brain cells from the effects of oxygen deprivation. The average time for starting magnesium treatment was 45 minutes after stroke symptoms began, and 74 percent of the patients were started on the treatment within an hour, the study authors noted.

The magnesium was safe, but did not provide any benefits, the researchers found. Ninety days after their stroke, the patients had slight to moderate levels of disability and required assistance to do many of their previous activities, according to findings presented Thursday at the American Stroke Association's International Stroke Conference in San Diego.

Research presented at medical meetings should be viewed as preliminary until published in a peer-reviewed journal.

In animal studies, magnesium was found to widen blood vessels in the brain and increase blood flow, offsetting the dangerous calcium build-up that occurs in cells that are starved of oxygen.

Earlier, small trials with patients showed that giving magnesium up to 12 hours after a stroke caused neither harm nor benefit. However, there were signs that magnesium might be helpful to those who received it within a few hours after their stroke.

"We hoped magnesium would be beneficial, but in any case the study was a success in demonstrating we can get a drug to patients in this early time frame when there is the greatest amount of threatened brain tissue that might still be saved," principal investigator Dr. Jeffrey Saver, director of the stroke center at the University of California, Los Angeles, said in a stroke association news release.

"There are lots of other promising agents in the pipeline that could be helpful, and we now have a system for testing and using them," he added.

Currently, the clot-busting drug tPA is the only immediate treatment for ischemic strokes, which are caused by blocked blood flow. But this drug can't be given until patients undergo brain scans to determine the nature of their stroke.

"Giving tPA in the ambulance before brain imaging is not an option -- it could harm patients having a bleeding type of stroke. Neuroprotective drugs can be delivered in the field as they are safe for both types of stroke," Saver explained in the news release.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about stroke.

SOURCE: American Stroke Association, news release, Feb. 13, 2014

Copyright © 2014 HealthDay. All rights reserved. URL:http://consumer.healthday.com/Article.asp?AID=684395

Resources from HONselect: HONselect is the HON's medical search engine. It retrieves scientific articles, images, conferences and web sites on the selected subject.
Brain
Association
Therapeutics
Blood
Research Personnel
Specialty Chemicals and Products
Oxygen
Cells
The list of medical terms above are retrieved automatically from the article.

Disclaimer: The text presented on this page is not a substitute for professional medical advice. It is for your information only and may not represent your true individual medical situation. Do not hesitate to consult your healthcare provider if you have any questions or concerns. Do not use this information to diagnose or treat a health problem or disease without consulting a qualified healthcare professional.
Be advised that HealthDay articles are derived from various sources and may not reflect your own country regulations. The Health On the Net Foundation does not endorse opinions, products, or services that may appear in HealthDay articles.


Home img About us img MediaCorner img HON newsletter img Site map img Ethical policies img Contact