Subsets of , involved in cell-mediated immune responses.
TH1 cells secrete
and gamma , which enhance cell-mediated
responses and inhibit both TH2 subset cell activity and
the humoral immune responses. TH1 is , produces IL2,
IFNgamma, TNFbeta, provides help to
in production, activates and CTL and stimulates hypersensitivities.
TH2 cells, the other subset of T-helper cells, are also involved in cell-mediated
immune responses. TH2 cell activity and secretions are thought to inhibit cell-mediated responses and to enhance
the humoral response.
TH2 cells produce , IL5, IL6, IL10 and IL13, which provide help to
and induce class
to and , as well as supporting