A condition in which the immune system is functioning at a lower than normal level.

Immunosuppressive Drugs
Immunosuppresant Drugs

Drugs that block the immune system's ability to fight infection or foreign substances that enter the body. Immunosuppressive drugs are given in order to prevent the rejection of transplanted organs, or to treat Crohn's disease , ulcerative colitis , neutropenia, rheumatoid arthritis and connective tissue disorders. In rheumatoid arthritis, these drugs are effective in reducing inflammation and thus less corticosteroids are required. However, these drugs have many side effects, such as liver disease, lung inflammation, increased susceptibility to infection and suppression of blood cell production.
Cyclophosphamide and the glucocorticoids are commonly used immunosuppressive drugs.