Definition: A general term encompassing lower MOTOR NEURON DISEASE; PERIPHERAL NERVOUS SYSTEM DISEASES; and certain MUSCULAR DISEASES. Manifestations include MUSCLE WEAKNESS; FASCICULATION; muscle ATROPHY; SPASM; MYOKYMIA; MUSCLE HYPERTONIA, myalgias, and MUSCLE HYPOTONIA. Synonym(s): Amyotonia Congenita / Oppenheim Disease / Cramp-Fasciculation Syndrome / Fasciculation-Cramp Syndrome, Benign / Narrow term(s): Motor Neuron Disease Muscular Atrophy, Spinal Muscular Diseases Muscular Disorders, Atrophic Neuromuscular Junction Diseases Peripheral Nervous System Diseases Fatigue Syndrome, Chronic Isaacs Syndrome Stiff-Person Syndrome
Subheadings: complications / diagnosis / embryology / epidemiology / etiology / metabolism / microbiology / surgery / therapy