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Polyendocrinopathies, Autoimmune
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Definition:
Autoimmune diseases affecting multiple endocrine organs. Type I is characterized by childhood onset and chronic mucocutaneous candidiasis (), while type II exhibits any combination of adrenal insufficiency (), lymphocytic thyroiditis (;), ; and gonadal failure. In both types organ-specific against a variety of have been detected. The type II syndrome differs from type I in that it is associated with and B8 haplotypes, onset is usually in adulthood, and candidiasis is not present.
Synonym(s):
Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal-Dystrophy /
Autoimmune Syndrome Type I, Polyglandular /
Autoimmune Syndrome Type II, Polyglandular /
Polyglandular Type I Autoimmune Syndrome /
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