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Werner Syndrome
Definition: An autosomal recessive disorder that causes premature aging in adults, characterized by sclerodermal skin changes, cataracts, subcutaneous calcification, muscular atrophy, a tendency to diabetes mellitus, aged appearance of the face, baldness, and a high incidence of neoplastic disease.

Synonym(s): Progeria, Adult / Werner's Syndrome / Adult Progeria / Syndrome, Werner / Syndrome, Werner's / Werners Syndrome
See also:
Progeria  RecQ Helicases   

MeSH 2010 © U.S. National Library of Medicine®.
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  More information from the Genetics Home Reference Website
What is Werner syndrome?
Werner syndrome is a rare disorder characterized by the dramatic, rapid appearance of aging. Individuals with this syndrome typically grow and develop normally until they reach puberty. The age of onset of Werner syndrome is variable, but an early sign is the lack of a teenage growth spurt, which results in short stature. Other signs and symptoms appear when affected individuals are in their twenties or thirties and include loss and graying of hair, hoarseness, thickening of the skin, and cloudy lenses (cataracts) in both eyes. Overall, people affected by Werner syndr ...

How common is Werner syndrome?
Werner syndrome is estimated to affect 1 in 200,000 individuals in the United States. In Japan, the syndrome occurs more often, affecting between 1 in 20,000 and 1 in 40,000 people.


More information from the Genetics Home Reference Website
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  Web resources for "Werner Syndrome"
  English (7)  French (3)  German (2)  Spanish (1)  Portuguese (1)  Italian (1)  

= Site with HON description   -   = Site with a robot description
info: enter the site: (click below) domain of the site:  
view the HON description of the site HONcode - Werner Syndrome | Cancer.Netwww.cancer.net  
view the HON description of the site HONcode - Werner syndrome - Genetics Home Referenceghr.nlm.nih.gov 2
view the robot description of the site rare-diseases — National Organization for Rare Disorderswww.rarediseases.org  
view the robot description of the site University of Washington Werner Syndrome Home Pagewww.pathology.washington.edu  
view the robot description of the site University of Washington Werner Syndrome Home Pagewww.wernersyndrome.org  
view the HON description of the site HONcode - Orphanet: Werner syndromewww.orpha.net 3
view the robot description of the site Whonamedit - Werner's syndromewww.whonamedit.com 2
 
 

See also: - Progeria

Broader term(s): - Genetic Diseases, Inborn - Congenital, Hereditary, and Neonatal Diseases and Abnormalities - Metabolic Diseases
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  Medical image(s) for "Werner Syndrome"
click below to enlargeWerner Syndrome (Chromosome 8)
www.ncbi.nlm.nih.gov
Copyright © NCBI - Genes and Disease Werner Syndrome (Chromosome 8)
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  Medical News for "Werner Syndrome"
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  Scientific articles from MEDLINE for "Werner Syndrome"
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Subheadings: complications / diagnosis / embryology / epidemiology / etiology / metabolism / microbiology / surgery / therapy

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  Clinical Trials for "Werner Syndrome"
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  Medical Conferences/Events for "Werner Syndrome"
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Subheadings: complications / diagnosis / embryology / epidemiology / etiology / metabolism / microbiology / surgery / therapy


  Broader term(s):
      Diseases
          Nutritional and Metabolic Diseases
              Metabolic Diseases
                  DNA Repair-Deficiency Disorders 
      Diseases
          Congenital, Hereditary, and Neonatal Diseases and Abnormalities
              Genetic Diseases, Inborn 

MeSH 2010 © U.S. National Library of Medicine®.

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