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Chediak-Higashi Syndrome
Definition: A form of phagocyte bactericidal dysfunction characterized by unusual oculocutaneous albinism, high incidence of lymphoreticular neoplasms, and recurrent pyogenic infections. In many cell types, abnormal lysosomes are present leading to defective pigment distribution and abnormal neutrophil functions. The disease is transmitted by autosomal recessive inheritance and a similar disorder occurs in the beige mouse, the Aleutian mink, and albino Hereford cattle.

Synonym(s): Chediak Higashi Syndrome / Syndrome, Chediak-Higashi /

Narrow term(s):
   Aleutian Mink Disease

See also:
Aleutian Mink Disease  Albinism   

MeSH 2010 © U.S. National Library of Medicine®.
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  Web resources for "Chediak-Higashi Syndrome"
  English (4)  French (3)  German (1)  Spanish (1)    Italian (1)  

= Site with HON description   -   = Site with a robot description
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view the robot description of the site Chediak-Higashi Syndrome Symptoms, Diagnosis, Treatments and Causes - RightDiagnosis.comwww.wrongdiagnosis.com  
view the HON description of the site HONcode - Chediak-Higashi syndrome: MedlinePlus Medical Encyclopediawww.nlm.nih.gov  
view the HON description of the site HONcode - Orphanet: Chediak Higashi syndromewww.orpha.net  
view the robot description of the site rare-diseases — National Organization for Rare Disorderswww.rarediseases.org  
 
 

See also: - Albinism

Broader term(s): - Hematologic Diseases
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  Medical image(s) for "Chediak-Higashi Syndrome"
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See also: - Albinism
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  Medical News for "Chediak-Higashi Syndrome"
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Broader term(s): - Hematologic Diseases

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  Scientific articles from MEDLINE for "Chediak-Higashi Syndrome"
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Subheadings: complications / diagnosis / embryology / epidemiology / etiology / metabolism / microbiology / surgery / therapy

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  Clinical Trials for "Chediak-Higashi Syndrome"
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Subheadings: complications / diagnosis / embryology / epidemiology / etiology / metabolism / microbiology / surgery / therapy


  Broader term(s):
      Diseases
          Immune System Diseases
              Immunologic Deficiency Syndromes
                  Phagocyte Bactericidal Dysfunction 
      Diseases
          Hemic and Lymphatic Diseases
              Hematologic Diseases
                  Leukocyte Disorders
                      Phagocyte Bactericidal Dysfunction 

MeSH 2010 © U.S. National Library of Medicine®.

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