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Wolff-Parkinson-White Syndrome
Definition: A form of ventricular pre-excitation characterized by a short PR interval and a long QRS interval with a delta wave. In this syndrome, atrial impulse conducts to the HEART VENTRICLES via an accessory pathway located between the wall of the right or left atria and the ventricles, known as the bundle of Kent. The inherited form can be caused by mutation of PRKAG2 gene encoding a gamma-2 regulatory subunit of AMP-activated protein kinase.

Synonym(s): WPW Syndrome / Wolf-Parkinson-White Syndrome / Syndrome, WPW / Syndrome, Wolf-Parkinson-White / Syndrome, Wolff-Parkinson-White / Wolf Parkinson White Syndrome / Wolff Parkinson White Syndrome
MeSH 2010 © U.S. National Library of Medicine®.
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  More information from the Genetics Home Reference Website
What is Wolff-Parkinson-White syndrome?
Wolff-Parkinson-White syndrome is a condition characterized by abnormal electrical pathways in the heart that cause a disruption of the heart's normal rhythm (arrhythmia).
The heartbeat is controlled by electrical signals that move through the heart in a highly coordinated way. A specialized cluster of cells called the atrioventricular node conducts electrical impulses from the heart's upper chambers (the atria) to the lower chambers (the ventricles). Impulses move through the atrioventricular node during each heartbeat, stimulating the ventricles to ...

How common is Wolff-Parkinson-White syndrome?
Wolff-Parkinson-White syndrome affects 1 to 3 in 1,000 people worldwide. Only a small fraction of these cases appear to run in families.

Wolff-Parkinson-White syndrome is a common cause of an arrhythmia known as paroxysmal supraventricular tachycardia. Wolff-Parkinson-White syndrome is the most frequent cause of this abnormal heart rhythm in the Chinese population, where it is responsible for more than 70 percent of cases.


More information from the Genetics Home Reference Website
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  Web resources for "Wolff-Parkinson-White Syndrome"
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view the robot description of the site Wolff Parkinson White Syndromewww.rjmatthewsmd.com 2
view the HON description of the site HONcode - Wolff-Parkinson-White syndrome | Better Health Channelwww.betterhealth.vic.gov.au  
view the robot description of the site BBC - Health: Wolff-Parkinson-White syndrome www.bbc.co.uk  
view the HON description of the site HONcode - Wolff-Parkinson-White syndrome: MedlinePlus Medical Encyclopediawww.nlm.nih.gov  
view the robot description of the site Whonamedit - Wolff-Parkinson-White syndrome (Louis Wolff)www.whonamedit.com  
view the HON description of the site HONcode - Orphanet: Wolff Parkinson White syndromewww.orpha.net  
view the HON description of the site HONcode - Wolff-Parkinson-White syndromewww.healthcentral.com  
view the robot description of the site Ehealthconnection | Health Informationwww.ehealthconnection.com  
view the robot description of the site rare-diseases — National Organization for Rare Disorderswww.rarediseases.org  
view the robot description of the site Electrocardiogram (ECG, EKG) librarywww.ecglibrary.com  
view the HON description of the site HONcode - Browse Conditions - Genetics Home Referenceghr.nlm.nih.gov  
view the HON description of the site HONcode - Popular Antibiotic May Raise Risk of Sudden Death | BioPortfolio.comwww.bioportfolio.com  
 
 

Broader term(s): - Pre-Excitation Syndromes - Arrhythmias, Cardiac - Heart Diseases - Cardiovascular Diseases - Heart Defects, Congenital

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Broader term(s): - Arrhythmias, Cardiac - Heart Diseases
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  Scientific articles from MEDLINE for "Wolff-Parkinson-White Syndrome"
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Broader term(s): - Arrhythmias, Cardiac - Cardiovascular Diseases

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Subheadings: complications / diagnosis / embryology / epidemiology / etiology / metabolism / microbiology / surgery / therapy


  Broader term(s):
      Diseases
          Congenital, Hereditary, and Neonatal Diseases and Abnormalities
              Congenital Abnormalities
                  Cardiovascular Abnormalities
                      Heart Defects, Congenital 
      Diseases
          Cardiovascular Diseases
              Heart Diseases
                  Arrhythmias, Cardiac
                      Pre-Excitation Syndromes 

MeSH 2010 © U.S. National Library of Medicine®.

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