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Duane Retraction Syndrome
Definition: A syndrome characterized by marked limitation of abduction of the eye, variable limitation of adduction and retraction of the globe, and narrowing of the palpebral fissure on attempted adduction. The condition is caused by aberrant innervation of the lateral rectus by fibers of the oculomotor nerve. There are three subtypes: type 1 (associated with loss of abduction), type 2 (associated with loss of adduction), and type 3 (loss of abduction and adduction). Two loci for Duane retraction syndrome have been located, one at chromosome 8q13 (DURS1) and another at chromosome 2q31(DURS2). It is usually caused by congenital hypoplasia of the abducens nerve or nucleus, but may rarely represent an acquired syndrome. (Adams et al., Principles of Neurology, 6th ed, p271; Miller et al., Clinical Neuro-Ophthalmology, 4th ed, p691)

Synonym(s): Duane Syndrome / Ocular Retraction Syndrome / Duane Retraction Syndrome, Type 1 / Duane Retraction Syndrome, Type 2 / Duane Retraction Syndrome, Type 3 / Duane's Syndrome / Okihiro Syndrome / Type 1 Duane Retraction Syndrome / Type 2 Duane Retraction Syndrome / Type 3 Duane Retraction Syndrome / Duanes Syndrome / Ocular Retraction Syndromes / Retraction Syndromes, Ocular / Syndrome, Duane / Syndrome, Duane's
See also:
Ophthalmoplegia   

MeSH 2010 © U.S. National Library of Medicine®.
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  Web resources for "Duane Retraction Syndrome"
  English (12)  French (3)        Italian (1)  

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view the HON description of the site HONcode - ASNOM - Association Amicale Santé Navale et d'Outre Merwww.asnom.org  
view the HON description of the site HONcode - ASNOM - Association Amicale Santé Navale et d'Outre Merwww.asnom.org  
view the robot description of the site Learning About Duane Syndromewww.genome.gov  
view the HON description of the site HONcode - EyeRounds.org: Case56 Duane Retraction Syndrome Globe Retractionwebeye.ophth.uiowa.edu  
view the HON description of the site HONcode - Orphanet: Duane syndromewww.orpha.net 4
view the robot description of the site Rare Disease Database — National Organization for Rare Disorderswww.rarediseases.org 2
  view the HON description of the site Duane Retraction Syndrome discussion listswww.egroups.com  
view the robot description of the site Whonamedit - Okihiro's syndromewww.whonamedit.com  
view the robot description of the site What is Duane's Syndrome? definition, causes, treatmentswww.strabismus.org  
 
 

See also: - Ophthalmoplegia

Broader term(s): - Ocular Motility Disorders - Central Nervous System Diseases - Nervous System Diseases - Eye Diseases, Hereditary - Eye Diseases
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  Medical image(s) for "Duane Retraction Syndrome"
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Broader term(s): - Nervous System Diseases - Eye Diseases
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Broader term(s): - Nervous System Diseases - Eye Diseases

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Broader term(s): - Ocular Motility Disorders - Central Nervous System Diseases - Nervous System Diseases - Eye Diseases

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Subheadings: complications / diagnosis / embryology / epidemiology / etiology / metabolism / microbiology / surgery / therapy


  Broader term(s):
      Diseases
          Congenital, Hereditary, and Neonatal Diseases and Abnormalities
              Genetic Diseases, Inborn
                  Eye Diseases, Hereditary 
      Diseases
          Eye Diseases
              Ocular Motility Disorders 
              Eye Diseases, Hereditary 
      Diseases
          Nervous System Diseases
              Cranial Nerve Diseases
                  Ocular Motility Disorders 

MeSH 2010 © U.S. National Library of Medicine®.

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