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Muscular Atrophy, Spinal
Definition: A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts. Diseases in this category include Werdnig-Hoffmann disease and later onset SPINAL MUSCULAR ATROPHIES OF CHILDHOOD, most of which are hereditary. (Adams et al., Principles of Neurology, 6th ed, p1089)

Synonym(s): Bulbospinal Neuronopathy / Oculopharyngeal Spinal Muscular Atrophy / Progressive Muscular Atrophy / Scapuloperoneal Form of Spinal Muscular Atrophy / Spinal Muscular Atrophy / Adult Spinal Muscular Atrophy / Adult-Onset Spinal Muscular Atrophy / Distal Spinal Muscular Atrophy / Muscular Atrophy, Adult Spinal / Myelopathic Muscular Atrophy / Myelopathic Muscular Atrophy, Progressive / Progressive Myelopathic Muscular Atrophy / Progressive Proximal Myelopathic Muscular Atrophy / Proximal Myelopathic Muscular Atrophy, Progressive / Spinal Muscular Atrophy, Distal / Spinal Muscular Atrophy, Oculopharyngeal / Spinal Muscular Atrophy, Scapuloperoneal Form / Adult Onset Spinal Muscular Atrophy / Atrophies, Progressive Muscular / Atrophy, Myelopathic Muscular / Atrophy, Progressive Muscular / Atrophy, Spinal Muscular / Bulbospinal Neuronopathies / Muscular Atrophies, Progressive / Muscular Atrophy, Myelopathic / Muscular Atrophy, Progressive / Neuronopathies, Bulbospinal / Neuronopathy, Bulbospinal / Progressive Muscular Atrophies

Narrow term(s):
   Bulbo-Spinal Atrophy, X-Linked    Spinal Muscular Atrophies of Childhood

MeSH 2010 © U.S. National Library of Medicine®.
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  More information from the Genetics Home Reference Website
What is spinal muscular atrophy?
Spinal muscular atrophy is a disorder that affects the control of muscle movement. It is caused by a loss of specialized nerve cells, called motor neurons, in the spinal cord and the part of the brain that is connected to the spinal cord (the brainstem). The loss of motor neurons leads to weakness and shrinkage (atrophy) of muscles used for activities such as crawling, walking, sitting up, and controlling head movement. In severe cases of spinal muscular atrophy, the muscles used for breathing and swallowing are affected.
Spinal muscular atrophy is divide ...

How common is spinal muscular atrophy?
Spinal muscular atrophy affects 1 in 6,000 to 1 in 10,000 people.


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  Web resources for "Muscular Atrophy, Spinal"
  English (24)  French (6)  German (1)  Spanish (5)  Portuguese (1)    

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view the robot description of the site Spinal Muscular Atrophy Symptoms, Diagnosis, Treatments and Causes - RightDiagnosis.comwww.wrongdiagnosis.com 6
view the HON description of the site HONcode - Spinal muscular atrophy - Genetics Home Referenceghr.nlm.nih.gov 6
view the HON description of the site HONcode - Spinal Muscular Atrophy: MedlinePluswww.nlm.nih.gov 2
view the HON description of the site HONcode - Safe Eats™ Allergy-Friendly Recipes – Kids With Food Allergies Recipes & Diet www.kidswithfoodallergies.org  
view the robot description of the site Spinal Muscular Atrophy Information Page: National Institute of Neurological Disorders and Stroke (NINDS)www.ninds.nih.gov 8
view the robot description of the site Spinal Muscular Atrophy / Family Villagewww.familyvillage.wisc.edu  
view the robot description of the site BBC - Health: Spinal muscular atrophy www.bbc.co.uk 2
view the robot description of the site Spinal Muscular Atrophy - Families of SMA – Research Support Hopewww.fsma.org 22
view the robot description of the site Resveratrol and spinal muscular atrophywww.ricercasma.it 22
view the HON description of the site HONcode - Orphanet: Diseases listwww.orpha.net 17
view the robot description of the site Spinal Muscular Atrophy (SMA) Program at Children's Hospital Bostonwww.childrenshospital.org  
view the robot description of the site Whonamedit - Aran-Duchenne spinal muscular atrophywww.whonamedit.com 7
view the robot description of the site Jennifer Trust for Spinal Muscular Atrophy (JTSMA) | SMAwww.jtsma.org.uk  
view the robot description of the site rare-diseases — National Organization for Rare Disorderswww.rarediseases.org 5
view the HON description of the site HONcode - necrotizing fasciitis | Health Topics | NutritionFacts.orgnutritionfacts.org  
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Broader term(s): - Spinal Cord Diseases - Central Nervous System Diseases - Nervous System Diseases - Motor Neuron Disease - Neurodegenerative Diseases - Neuromuscular Diseases
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  Medical image(s) for "Muscular Atrophy, Spinal"
click below to enlargeGenes and disease - Spinal muscular atrophy
www.ncbi.nlm.nih.gov
Copyright © National Center for Biotechnology Information Genes and disease - Spinal muscular atrophy
Broader term(s): - Nervous System Diseases
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  Medical News for "Muscular Atrophy, Spinal"
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Broader term(s): - Nervous System Diseases

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  Scientific articles from MEDLINE for "Muscular Atrophy, Spinal"
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Subheadings: complications / diagnosis / embryology / epidemiology / etiology / metabolism / microbiology / surgery / therapy

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Broader term(s): - Neurodegenerative Diseases

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Subheadings: complications / diagnosis / embryology / epidemiology / etiology / metabolism / microbiology / surgery / therapy


  Broader term(s):
      Diseases
          Nervous System Diseases
              Neuromuscular Diseases 
                  Motor Neuron Disease 
              Neurodegenerative Diseases
                  Motor Neuron Disease 
      Diseases
          Nervous System Diseases
              Central Nervous System Diseases
                  Spinal Cord Diseases 

MeSH 2010 © U.S. National Library of Medicine®.

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