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Pick Disease of the Brain
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Definition:
A rare form of that is sometimes familial. Clinical features include ; ; ; ; memory loss; and personality deterioration. This pattern is consistent with the pathologic findings of circumscribed atrophy of the poles of the and . Neuronal loss is maximal in the , entorhinal cortex, and . Some ballooned cortical neurons contain argentophylic (Pick) bodies. (From Brain Pathol 1998 Apr;8(2):339-54; Adams et al., Principles of Neurology, 6th ed, pp1057-9)
Synonym(s):
Circumscribed Lobar Atrophy of the Brain /
Lobar Atrophy (Brain) /
Brain Atrophy, Circumscribed Lobar /
Pick Disease /
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