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Hallervorden-Spatz Syndrome
Definition: A rare autosomal recessive degenerative disorder which usually presents in late childhood or adolescence. Clinical manifestations include progressive MUSCLE SPASTICITY; hyperreflexia; MUSCLE RIGIDITY; DYSTONIA; DYSARTHRIA; and intellectual deterioration which progresses to severe dementia over several years. Pathologic examination reveals neuronal atrophy in the globus pallidus and iron deposition in blood vessels and perivascular spaces. (From Adams et al., Principles of Neurology, 6th ed, p972; Davis & Robertson, Textbook of Neuropathology, 2nd ed, pp972-929)

Synonym(s): Pigmentary Pallidal Degeneration / Hallervorden-Spatz Disease / Pigmentary Pallidal Atrophy / Atrophies, Pigmentary Pallidal / Atrophy, Pigmentary Pallidal / Degeneration, Pigmentary Pallidal / Degenerations, Pigmentary Pallidal / Hallervorden Spatz Disease / Hallervorden Spatz Syndrome / Pallidal Atrophies, Pigmentary / Pallidal Atrophy, Pigmentary / Pallidal Degenerations, Pigmentary / Pigmentary Pallidal Atrophies / Pigmentary Pallidal Degenerations
MeSH 2010 © U.S. National Library of Medicine®.
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  Web resources for "Hallervorden-Spatz Syndrome"
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view the robot description of the site Hallervorden-Spatz disease Symptoms, Diagnosis, Treatments and Causes - RightDiagnosis.comwww.wrongdiagnosis.com  
view the robot description of the site Whonamedit - Hallervorden-Spatz syndromewww.whonamedit.com 2
view the HON description of the site HONcode - Hallervorden-Spatz diseasewww.healthcentral.com  
view the robot description of the site Consumer Health Informationhealthlink.mcw.edu  
view the HON description of the site HONcode - Hallervorden-Spatz disease: MedlinePlus Medical Encyclopediawww.nlm.nih.gov  
view the robot description of the site rare-diseases — National Organization for Rare Disorderswww.rarediseases.org  
view the HON description of the site HONcode - H - He Medical Dictionary Indexwww.drugs.com  
view the robot description of the site NBIA Disorders Associationwww.nbiadisorders.org  
 
 

Broader term(s): - Basal Ganglia Diseases - Brain Diseases - Central Nervous System Diseases - Nervous System Diseases - Neuroaxonal Dystrophies - Movement Disorders - Neurodegenerative Diseases

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  Medical image(s) for "Hallervorden-Spatz Syndrome"
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Broader term(s): - Brain Diseases - Nervous System Diseases
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  Medical News for "Hallervorden-Spatz Syndrome"
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Broader term(s): - Nervous System Diseases

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  Scientific articles from MEDLINE for "Hallervorden-Spatz Syndrome"
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Subheadings: complications / diagnosis / embryology / epidemiology / etiology / metabolism / microbiology / surgery / therapy

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  Clinical Trials for "Hallervorden-Spatz Syndrome"
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Broader term(s): - Basal Ganglia Diseases - Brain Diseases - Central Nervous System Diseases - Nervous System Diseases - Movement Disorders - Neurodegenerative Diseases

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Broader term(s): - Movement Disorders

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Subheadings: complications / diagnosis / embryology / epidemiology / etiology / metabolism / microbiology / surgery / therapy


  Broader term(s):
      Diseases
          Congenital, Hereditary, and Neonatal Diseases and Abnormalities
              Genetic Diseases, Inborn
                  Heredodegenerative Disorders, Nervous System 
      Diseases
          Nervous System Diseases
              Neurodegenerative Diseases
                  Heredodegenerative Disorders, Nervous System 
              Central Nervous System Diseases
                  Movement Disorders 
                  Brain Diseases
                      Neuroaxonal Dystrophies 
      Diseases
          Nervous System Diseases
              Central Nervous System Diseases
                  Brain Diseases
                      Basal Ganglia Diseases 

MeSH 2010 © U.S. National Library of Medicine®.

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