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Cystic Fibrosis
Definition: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.

Synonym(s): Mucoviscidosis / Fibrocystic Disease of Pancreas / Pancreatic Cystic Fibrosis / Pulmonary Cystic Fibrosis / Cystic Fibrosis, Pancreatic / Cystic Fibrosis, Pulmonary / Fibrosis, Cystic / Pancreas Fibrocystic Disease / Pancreas Fibrocystic Diseases
See also:
Cystic Fibrosis Transmembrane Conductance Regulator  Mice, Inbred CFTR  Sweating 

MeSH 2010 © U.S. National Library of Medicine®.
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  More information from the Genetics Home Reference Website
What is cystic fibrosis?
Cystic fibrosis is an inherited disease of the mucus glands that affects many body systems. In particular, this disorder causes progressive damage to the respiratory system and chronic digestive system problems.
Mucus is a slippery substance that lubricates and protects the linings of the airways, digestive system, reproductive system, and other organs and tissues. In people with cystic fibrosis, the body produces mucus that is abnormally thick and sticky. This abnormal mucus can obstruct the airways, leading to severe problems with breathing and bacterial infecti ...

How common is cystic fibrosis?
Cystic fibrosis is a common genetic disease in the Caucasian (white) population in the United States. The disease occurs in about 1 in 3,200 Caucasian newborns. Cystic fibrosis is less common in other ethnic groups, affecting 1 in 15,000 African Americans and 1 in 31,000 Asian Americans.


More information from the Genetics Home Reference Website
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  Web resources for "Cystic Fibrosis"
  English (100)  French (93)  German (20)  Spanish (14)  Portuguese (2)  Italian (18)  Dutch (1)

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view the robot description of the site Cystic Fibrosis - Symptoms, Causes, Treatments - Better Medicinewww.wrongdiagnosis.com 4
view the HON description of the site HONcode - ASNOM - Association Amicale Santé Navale et d'Outre Merwww.asnom.org  
view the HON description of the site HONcode - Cystic Fibrosis: MedlinePluswww.nlm.nih.gov 22
view the HON description of the site HONcode - Introduction: Cystic Fibrosis - CureResearch.comwww.cureresearch.com  
view the robot description of the site Cystic Fibrosis Information | What is Cystic Fibrosiswww.iacfa.org  
view the robot description of the site Annotated Bibliography : Research & Evidence : The Vest® Airway Clearance Systemwww.thevest.com 3
view the HON description of the site HONcode - Cystic fibrosis - Genetics Home Referenceghr.nlm.nih.gov 7
view the robot description of the site Cystic Fibrosis - Cedars-Sinaiwww.cedars-sinai.edu  
view the HON description of the site HONcode - DISEASES OF INFANCY AND CHILDHOOD www.pathguy.com  
view the HON description of the site HONcode - Cure for Plague - Daypro Side Effects Articleswww.emedtv.com  
view the robot description of the site IOH Diabetes and related disorders - Cystic Fibrosis (CF)www.isletsofhope.com 2
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See also: - Cystic Fibrosis Transmembrane Conductance Regulator - Sweating

Broader term(s): - Pancreatic Diseases - Digestive System Diseases - Lung Diseases - Respiratory Tract Diseases - Genetic Diseases, Inborn - Congenital, Hereditary, and Neonatal Diseases and Abnormalities
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  Medical image(s) for "Cystic Fibrosis"
click below to enlargeCystic Fibrosis
www.ncbi.nlm.nih.gov
Copyright © NCBI - Genes and Disease Cystic Fibrosis
click below to enlargeChlorid transport and Cystic Fibrosis
student.biology.arizona.edu
Copyright © University of Arizona: Student Project Chlorid transport and Cystic Fibrosis
click below to enlargeCystic Fibrosis
www.orlive.com
Copyright © ORLive Cystic Fibrosis
click below to enlargeCystic Fibrosis - 3D Medical Animation
www.virtualrespiratorycentre.com
Copyright © Virtual Respiratory Centre Cystic Fibrosis - 3D Medical Animation
Broader term(s): - Infant, Newborn, Diseases
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  Medical News for "Cystic Fibrosis"
Azithromycin Doesn't Always Help Lungs in Cystic Fibrosis Patients   (05/04/2010, HealthDay)
Pigs Yield Clues to Cystic Fibrosis-Related Lung Disease   (04/28/2010, HealthDay)
Drug Improved Survival in Mice With Cystic Fibrosis   (02/19/2010, HealthDay)
Wider Adult Screening May Mean Fewer Children With Cystic Fibrosis   (12/15/2009, HealthDay)
Stem Cells May Offer Alternative to Lung Transplants   (11/06/2009, HealthDay)
Gene 'Switch' May Help Drive Excess Fluid in Lungs   (09/15/2009, HealthDay)
Gene Linked to Liver Disease in Cystic Fibrosis   (09/08/2009, HealthDay)
Zenpep Approved for Pancreatic Disorder   (08/28/2009, HealthDay)
Cystic Fibrosis Treatment May Cause Hearing Loss   (07/02/2009, HealthDay)
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Broader term(s): - Pancreatic Diseases - Lung Diseases

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  Scientific articles from MEDLINE for "Cystic Fibrosis"
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  Clinical Trials for "Cystic Fibrosis"
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See also: - Sweating

Broader term(s): - Pancreatic Diseases - Digestive System Diseases - Lung Diseases - Respiratory Tract Diseases - Congenital, Hereditary, and Neonatal Diseases and Abnormalities

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  Medical Conferences/Events for "Cystic Fibrosis"
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Subheadings: complications / diagnosis / embryology / epidemiology / etiology / metabolism / microbiology / surgery / therapy


  Broader term(s):
      Diseases
          Congenital, Hereditary, and Neonatal Diseases and Abnormalities
              Infant, Newborn, Diseases 
              Genetic Diseases, Inborn 
      Diseases
          Respiratory Tract Diseases
              Lung Diseases 
      Diseases
          Digestive System Diseases
              Pancreatic Diseases 

MeSH 2010 © U.S. National Library of Medicine®.

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