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Isaacs Syndrome
Definition: A rare neuromuscular disorder with onset usually in late childhood or early adulthood, characterized by intermittent or continuous widespread involuntary muscle contractions; FASCICULATION; hyporeflexia; MUSCLE CRAMP; MUSCLE WEAKNESS; HYPERHIDROSIS; TACHYCARDIA; and MYOKYMIA. Involvement of pharyngeal or laryngeal muscles may interfere with speech and breathing. The continuous motor activity persists during sleep and general anesthesia (distinguishing this condition from STIFF-PERSON SYNDROME). Familial and acquired (primarily autoimmune) forms have been reported. (From Ann NY Acad Sci 1998 May 13;841:482-496; Adams et al., Principles of Neurology, 6th ed, p1491)

Synonym(s): Myokymia, Continuous / Neuromyotonia / Pseudomyotonia / Acquired Neuromyotonia / Continuous Muscle Activity Syndrome / Gamstorp-Wohlfart Syndrome / Isaacs' Syndrome / Isaacs-Mertens Syndrome / Pseudomyotonia Syndrome of Isaacs / Quantal Squander / Syndrome of Continuous Muscle Activity / Continuous Myokymia / Continuous Myokymias / Gamstorp Wohlfart Syndrome / Gamstorp-Wohlfart Syndromes / Isaac Syndrome / Isaacs Mertens Syndrome / Isaacs Pseudomyotonia Syndrome / Myokymias, Continuous / Neuromyotonia, Acquired / Syndromes, Gamstorp-Wohlfart / Syndromes, Isaacs-Mertens
MeSH 2010 © U.S. National Library of Medicine®.
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  Web resources for "Isaacs Syndrome"
  English (5)  French (1)          

= Site with HON description   -   = Site with a robot description
info: enter the site: (click below) domain of the site:  
view the robot description of the site Isaac's Syndrome Information Page: National Institute of Neurological Disorders and Stroke (NINDS)www.ninds.nih.gov 2
view the HON description of the site HONcode - Orphanet: Isaac's syndromewww.orpha.net  
view the robot description of the site Rare Disease Database — National Organization for Rare Disorderswww.rarediseases.org  
view the robot description of the site Whonamedit - Hoffmann's syndrome (Johann Hoffmann)www.whonamedit.com  
 
 

Broader term(s): - Muscular Diseases - Musculoskeletal Diseases - Neuromuscular Diseases - Nervous System Diseases - Peripheral Nervous System Diseases

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  Medical image(s) for "Isaacs Syndrome"
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Broader term(s): - Nervous System Diseases
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  Medical News for "Isaacs Syndrome"
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Broader term(s): - Muscular Diseases - Nervous System Diseases

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  Scientific articles from MEDLINE for "Isaacs Syndrome"
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Subheadings: complications / diagnosis / embryology / epidemiology / etiology / metabolism / microbiology / surgery / therapy

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  Clinical Trials for "Isaacs Syndrome"
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Broader term(s): - Muscular Diseases - Musculoskeletal Diseases - Neuromuscular Diseases - Nervous System Diseases - Peripheral Nervous System Diseases

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  Medical Conferences/Events for "Isaacs Syndrome"
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Subheadings: complications / diagnosis / embryology / epidemiology / etiology / metabolism / microbiology / surgery / therapy


  Broader term(s):
      Diseases
          Nervous System Diseases
              Neuromuscular Diseases
                  Peripheral Nervous System Diseases 
      Diseases
          Musculoskeletal Diseases
              Muscular Diseases 

MeSH 2010 © U.S. National Library of Medicine®.

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