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Lambert-Eaton Myasthenic Syndrome
Definition: An autoimmune disease characterized by weakness and fatigability of proximal muscles, particularly of the pelvic girdle, lower extremities, trunk, and shoulder girdle. There is relative sparing of extraocular and bulbar muscles. CARCINOMA, SMALL CELL of the lung is a frequently associated condition, although other malignancies and autoimmune diseases may be associated. Muscular weakness results from impaired impulse transmission at the NEUROMUSCULAR JUNCTION. Presynaptic calcium channel dysfunction leads to a reduced amount of acetylcholine being released in response to stimulation of the nerve. (From Adams et al., Principles of Neurology, 6th ed, pp 1471)

Synonym(s): Eaton-Lambert Syndrome / Myasthenic Syndrome, Lambert-Eaton / Eaton-Lambert Myasthenic Syndrome / Lambert-Eaton Syndrome / Myasthenic-Myopathic Syndrome of Eaton-Lambert / Myasthenic-Myopathic Syndrome of Lambert-Eaton / Myopathic-Myasthenic Syndrome of Eaton-Lambert / Myopathic-Myasthenic Syndrome of Lambert-Eaton / Eaton Lambert Myasthenic Syndrome / Eaton Lambert Syndrome / Eaton-Lambert Myasthenic-Myopathic Syndrome / Eaton-Lambert Myopathic-Myasthenic Syndrome / Eaton-Lambert Myopathic-Myasthenic Syndromes / Lambert Eaton Myasthenic Syndrome / Lambert Eaton Syndrome / Lambert-Eaton Myasthenic-Myopathic Syndrome / Lambert-Eaton Myasthenic-Myopathic Syndromes / Lambert-Eaton Myopathic-Myasthenic Syndrome / Lambert-Eaton Myopathic-Myasthenic Syndromes / Myasthenic Myopathic Syndrome of Eaton Lambert / Myasthenic Myopathic Syndrome of Lambert Eaton / Myasthenic Syndrome, Eaton-Lambert / Myasthenic Syndrome, Lambert Eaton / Myopathic Myasthenic Syndrome of Eaton Lambert / Syndrome, Eaton-Lambert / Syndrome, Eaton-Lambert Myasthenic / Syndrome, Lambert-Eaton / Syndrome, Lambert-Eaton Myasthenic
MeSH 2010 © U.S. National Library of Medicine®.
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  Web resources for "Lambert-Eaton Myasthenic Syndrome"
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view the robot description of the site Lambert-Eaton Syndrome or Eaton-Lambert Syndromewww.virtualneurocentre.com  
view the robot description of the site Lambert-Eaton Myasthenic Syndrome Information Page: National Institute of Neurological Disorders and Stroke (NINDS)www.ninds.nih.gov  
view the HON description of the site HONcode - Lambert-Eaton Syndromewww.healthcentral.com  
view the HON description of the site HONcode - Lambert-Eaton syndrome: MedlinePlus Medical Encyclopediawww.nlm.nih.gov 2
view the robot description of the site Orphanet Journal of Rare Diseases | Full text | Paraneoplastic neurological syndromeswww.ojrd.com  
view the robot description of the site LEMS.com, Lambert-Eaton Myasthenic Syndrome: Causewww.lems.com 4
view the HON description of the site HONcode - Orphanet: Lambert Eaton myasthenic syndromewww.orpha.net 2
view the robot description of the site rare-diseases — National Organization for Rare Disorderswww.rarediseases.org  
 
 

Broader term(s): - Paraneoplastic Syndromes, Nervous System - Nervous System Neoplasms - Neoplasms - Nervous System Diseases - Neuromuscular Diseases - Autoimmune Diseases - Immune System Diseases

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Broader term(s): - Neoplasms - Nervous System Diseases
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Broader term(s): - Neoplasms - Autoimmune Diseases of the Nervous System - Nervous System Diseases

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Broader term(s): - Nervous System Neoplasms - Neoplasms - Autoimmune Diseases of the Nervous System - Nervous System Diseases - Neuromuscular Diseases - Autoimmune Diseases - Immune System Diseases

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Subheadings: complications / diagnosis / embryology / epidemiology / etiology / metabolism / microbiology / surgery / therapy


  Broader term(s):
      Diseases
          Immune System Diseases
              Autoimmune Diseases 
                  Autoimmune Diseases of the Nervous System 
      Diseases
          Nervous System Diseases
              Neuromuscular Diseases
                  Neuromuscular Junction Diseases 
              Neurodegenerative Diseases
                  Paraneoplastic Syndromes, Nervous System 
              Autoimmune Diseases of the Nervous System 
      Diseases
          Neoplasms
              Paraneoplastic Syndromes
                  Paraneoplastic Syndromes, Nervous System 
              Neoplasms by Site
                  Nervous System Neoplasms
                      Paraneoplastic Syndromes, Nervous System 

MeSH 2010 © U.S. National Library of Medicine®.

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