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Hierarchy  - English - French - German - Spanish - Portuguese - Italian - Dutch    Colorectal Neoplasms, Hereditary Nonpolyposis Definition: A group of autosomal-dominant inherited diseases in which COLON CANCER arises in discrete adenomas. Unlike FAMILIAL POLYPOSIS COLI with hundreds of polyps, hereditary nonpolyposis colorectal neoplasms occur much later, in the fourth and fifth decades. HNPCC has been associated with germline mutations in mismatch repair (MMR) genes. Synonym(s): Hereditary Nonpolyposis Colorectal Cancer / Hereditary Nonpolyposis Colorectal Neoplasms / Lynch Syndrome / Colon Cancer, Familial Nonpolyposis / MeSH 2010 © U.S. National Library of Medicine®. Browse - New search

More information from the Genetics Home Reference Website What is hereditary nonpolyposis colorectal cancer? Hereditary nonpolyposis colorectal cancer, often called HNPCC or Lynch syndrome, is a type of inherited cancer of the digestive tract, particularly the colon (large intestine) and rectum. People with hereditary nonpolyposis colorectal cancer have an increased risk of cancers of the stomach, small intestine, liver, gallbladder ducts, upper urinary tract, brain, skin, and prostate. Women with this disorder also have a greatly increased risk of endometrial and ovarian cancer. Even though the disorder is described using the term nonpolyposis, peo ... How common is hereditary nonpolyposis colorectal cancer? In the United States, about 160,000 new cases of colorectal cancer are diagnosed each year. Hereditary nonpolyposis colorectal cancer is responsible for approximately 2 percent to 7 percent of all diagnosed cases of colorectal cancer. More information from the Genetics Home Reference Website © Genetics Home Reference Browse - New search       Web resources for "Colorectal Neoplasms, Hereditary Nonpolyposis"   English (14)  French (3)  German (1)         = Site with HON description   -   = Site with a robot description info: enter the site: (click below) domain of the site:   HONcode - Lynch syndrome - Genetics Home Reference ghr.nlm.nih.gov 5 Lynch syndrome - MayoClinic.com www.mayoclinic.com   BBC - Health: Lynch syndrome www.bbc.co.uk 2 Whonamedit - Lynch's syndrome I and II www.whonamedit.com   Eyes on the Prize: Frequently Asked Questions about Gynecologic Cancers: Answers from the Pros: Cervical, Endometrial, Ovarian, Uterine, Gestational, Vulvar, Va... www.eyesontheprize.org   HONcode - Hereditary Cancer Program : BC Cancer Agency www.bccancer.bc.ca   Genomics|Update|Current www.cdc.gov 2 Colon Cancer | MD Anderson Cancer Center www.mdacc.tmc.edu   Annals of Internal Medicine | Page Not Found www.annals.org   Genetic Health Glossary www.genetichealth.com 2 Katie Couric Colon Cancer Shows... www.coloncancerresource.com   HONcode - http://www.healthatoz.com/healthatoz/Ato... www.healthatoz.com 9 Mid-Atlantic Cancer Genetics Network - Colon Cancer Study, colon cancer research, hereditary colon cancer www.macgn.org   Broader term(s): - Colorectal Neoplasms - Intestinal Neoplasms - Gastrointestinal Neoplasms - Digestive System Neoplasms - Neoplasms - Neoplastic Syndromes, Hereditary - Metabolic Diseases - Nutritional and Metabolic Diseases Browse - New search       Medical image(s) for "Colorectal Neoplasms, Hereditary Nonpolyposis" No results for this term. Browse other medical images in HONmedia? Broader term(s): - Colorectal Neoplasms - Intestinal Neoplasms - Neoplasms Browse - New search       Medical News for "Colorectal Neoplasms, Hereditary Nonpolyposis" No results for this term. More health news Broader term(s): - Colorectal Neoplasms - Neoplasms Browse - New search       Scientific articles from MEDLINE for "Colorectal Neoplasms, Hereditary Nonpolyposis"   - English - French - German - Spanish - Portuguese - Italian - Dutch     All recent articles  Therapy:  by recall    /  by precision  Diagnosis:  by recall    /  by precision  Etiology:  by recall    /  by precision  Prognosis:  by recall    /  by precision Subheadings: chemistry / complications / diagnosis / embryology / epidemiology / etiology / metabolism / microbiology / surgery / therapy Browse - New search       Clinical Trials for "Colorectal Neoplasms, Hereditary Nonpolyposis" ClinicalTrials.gov - Linking patients to medical research Capsule Endoscopy to Screen for Small Bowel Neoplasia in Lynch Syndrome CHROENDOHNPCC: Early Detection of Pre-Cancer Lesions in Adults With Hereditary Nonpolyposis Colorectal Cancer Syndrome Intrauterine Levonorgestrel and Observation or Observation Alone in Preventing Atypical Endometrial Hyperplasia and Endometrial Cancer in Women With Hereditary Non-Polyposis Colorectal Cancer or Lynch Syndrome Broader term(s): - Colorectal Neoplasms - Intestinal Neoplasms - Gastrointestinal Neoplasms - Digestive System Neoplasms - Neoplasms - Metabolic Diseases Browse - New search       Medical Conferences/Events for "Colorectal Neoplasms, Hereditary Nonpolyposis" No results for this term. Consult HON's world-wide database of medical meetings Browse - New search       Refine the search for  "Colorectal Neoplasms, Hereditary Nonpolyposis" Subheadings: chemistry / complications / diagnosis / embryology / epidemiology / etiology / metabolism / microbiology / surgery / therapy   Broader term(s):       Diseases           Nutritional and Metabolic Diseases               Metabolic Diseases                   DNA Repair-Deficiency Disorders        Diseases           Congenital, Hereditary, and Neonatal Diseases and Abnormalities               Genetic Diseases, Inborn                   Neoplastic Syndromes, Hereditary        Diseases           Digestive System Diseases               Gastrointestinal Diseases                   Intestinal Diseases                       Intestinal Neoplasms                           Colorectal Neoplasms                        Colonic Diseases                           Colorectal Neoplasms                    Gastrointestinal Neoplasms                       Intestinal Neoplasms                           Colorectal Neoplasms        Diseases           Digestive System Diseases               Digestive System Neoplasms                   Gastrointestinal Neoplasms                       Intestinal Neoplasms                           Colorectal Neoplasms        Diseases           Neoplasms               Neoplastic Syndromes, Hereditary                Neoplasms by Site                   Digestive System Neoplasms                       Gastrointestinal Neoplasms                           Intestinal Neoplasms                               Colorectal Neoplasms  MeSH 2010 © U.S. National Library of Medicine®. 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