Definition:
A rare form of non-Hodgkin lymphoma having a usually diffuse pattern with both small and medium lymphocytes and small cleaved cells. It accounts for about 5% of adult non-Hodgkin lymphomas in the United States and Europe. The majority of mantle-cell lymphomas are associated with a t(11;14) translocation resulting in overexpression of the cyclin D1 gene ().
Synonym(s):
Lymphocytic Lymphoma, Diffuse, Poorly-Differentiated /
Lymphoma, Centrocytic Small-Cell /
Lymphoma, Lymphocytic, Diffuse, Intermediate Differentiated /
Lymphoma, Lymphocytic, Diffuse, Poorly-Differentiated /